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Bacterial Resistance
Mechanisms of Bacterial Reistance and antibiotic examples
10
Other
Professional
09/16/2012

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Cards

Term
Hydrolytic enzymatic bacterial resistance
Definition
B-lactams (PCN's and Cephs)
Term
Modifying enzymes: acetylation, adenylation, phosphorylation bacterial resistance
Definition
aminoglycosides and chloramp
Term
Beta lactamase inhibitors (do not fall victim to enzymatic resistance)
Definition
tazobactam, augmentin, clavulante acid
Term
Reduced permeability bacterial resistance
Definition
aminoglycosides, quinolones, B-lactams, TMP, chloramp
Term
Alteration of Target Sites: penicillin-binding proteins (PBP)bacterial resistance
Definition
B-lactams (PCN and Cephs)
Term
Alteration of Target Sites: DNA gyrase bacterial resistance
Definition
quinolones
Term
Alteration of Target Sites: Ribosomal RNA bacterial resistance
Definition
macrolides, clindamycin
Term
Alteration of Target Sites: RNA polymerase bacterial resistance
Definition
Rifampin
Term
Alteration of Target Sites: Enzyme Target bacterial resistance
Definition
TMP/SMX
Term
Efflux pumps (increased efflux) bacterial resistance
Definition
Tetracyclines, macrolides, quinolones
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