Term
| What is the MOA for Alpha 1 receptors? |
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Definition
| Activates phospholipase C which increases inositol triphosphates and Ca2+ levels |
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Term
| What is the MOA for Alpha 2 receptors? |
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Definition
| Inhibits Adenylyl cyclase to decrease cyclic AMP levels |
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Term
| What is the MOA for Beta 1 receptors? |
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Definition
| Stimulates adenylyl cyclase to increase cyclic AMP levels |
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Term
| What is the MOA for Beta 2 receptors? |
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Definition
| Stimulates adenylyl cyclase to increase cyclic AMP levels |
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Term
| What is the MOA for Nicotinic receptors? |
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Definition
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Term
| What is the MOA for Muscarininc receptors? |
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Definition
| Activates phospholipase C which increases inositol triphosphates and Ca2+ levels |
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Term
| What tissues use Alpha 1 receptors |
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Definition
| Radial muscle of the iris, vascular smooth muscle tissue, and GI tract. |
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Term
| What tissues use Alpha 2 receptors |
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Definition
| Ciliary body vasculature, Presynaptic neurons of the sympathetic system, GI tract wall |
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Term
| What tissues use Beta 1 receptors |
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Definition
| Non-pigmented ciliary epithelium, Heart, kidneys, salivary glands, adipose tissue |
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Term
| What tissues use Beta 2 receptors |
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Definition
| Non-pigmented ciliary epithelium, ciliary muscle (dominate in the eye), Bronchioles, GI tract, Bladder wall, Vascular smooth muscle, |
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Term
| What tissues use Nicotinic receptors |
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Definition
| Neuromuscular junction, sympathetic and parasympathetic ganglia |
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Term
| What tissues use Muscarinic receptors? |
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Definition
| Bronchioles, sphincter muscle of the iris, ciliary muscle, lacrimal gland |
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Term
| What are the three parasympathetic effects? |
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Definition
| 1. SLUD, 2. Bronchoconstriction, miosis, accommodation, 3. Rest and Digest |
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