Term
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Definition
| Muscarinic/Nicotinic AGONIST. Long lasting |
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Term
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Definition
| AChE (Acetylcholine Esterase) Inhibitor |
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Term
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Definition
| Nicotinic (nerve) ANTAGONIST |
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Term
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Definition
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Term
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Definition
| selective muscarinic AGONIST |
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Term
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Definition
| Nicotinic muscle (Nm) ANTAGONIST |
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Term
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Definition
| Blocks choline uptake. No clinical use |
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Term
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Definition
| Destroys SNARE proteins, prevents transmitter release |
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Term
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Definition
| Botulinum A toxin. Treats muscle spasms, dystonias, strabismus, achalasia |
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Term
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Definition
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Term
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Definition
| β1- and β2 AGONIST (not used clinicaly) |
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Term
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Definition
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Term
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Definition
| Blocks UPTAKE 1, NE released from UPTAKE 1 (NET) |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| Blocks release of NE from nerve cell |
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Term
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Definition
| Inhibits synthesis of DA (thus inhibiting synthesis of NE) |
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Term
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Definition
| Destroys vesicle, depletes NE |
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Term
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Definition
| creates false transmitter (alpha-mNE)which acts centrally as an alpha-2 agonist, reducing central sympathetic outflow. |
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Term
| Norepinephrine affects which receptors? |
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Definition
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Term
| Phenylphrine affects which receptors? |
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Definition
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Term
| Terbutaline affects which receptors? |
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Definition
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Term
| Dobutamine affects which receptors? |
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Definition
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Term
| Clonidine affects which receptors? |
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Definition
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Term
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Definition
| muscarinic antagonist (mAChR antagonist) |
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Term
| Which drug may cause 'epi-reversal', a drop in blood pressure, if administered before Epinephrine? |
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Definition
| Phentolamine (alpha-1 blocker), which prevents vascular constriction |
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Term
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Definition
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Term
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Definition
| Beta-2 AGONIST, used for acute asthma |
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Term
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Definition
| Beta-2 AGONIST, for chronic asthma, always given with a steroid |
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Term
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Definition
| Beta-2 AGONIST, for chronic asthma, always given with a steroid |
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Term
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Definition
| Beta 2 AGONIST, relaxes uterus, to delay delivery of premature babies |
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Term
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Definition
| Beta-1 agonist. Low doses: vomiting and increased renal blood flow. Medium doses: Beta-1 AGONIST. High doses: local ischemia |
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Term
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Definition
| Beta-1 AGONIST, no vomiting, no ischemia, no renal blood flow increase |
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Term
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Definition
| Dopamine ANTAGONIST, blocks D1 receptor |
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Term
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Definition
| Indirect sympathomimetic- converted to octopamine, an inert/false transmitter. Can cause hypertension. |
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Term
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Definition
| 'Amphetamine-like' Indirectly releases NE, direct Beta-2 agonist and alpha-1 agonist. Anorexigenic |
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Term
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Definition
| "Amphetamine like", lacks direct Beta-2 agonist action. Indirectly acts as a nasal decongestant. Has less CNS stimulation than ephedrine. |
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Term
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Definition
| Both 'D' and 'L' isomers. Act the same in the periphery to indirectly release NE. In CNS D isomer is 3-4x more potent. Releases DA to stimulate CNS. |
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Term
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Definition
| 'Ectasy' - can cause hyperthermia |
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Term
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Definition
| Last longer than cocaine, shorter than amphetamine |
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Term
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Definition
| 'Amphetamine like'. Local anesthetic, and vasoconstricter. Blocks NE reuptake in periphery and DA reuptake in CNS. |
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Term
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Definition
| Irreversibly binding, non-selective alpha-1 and alpha-2 antagonist |
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Term
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Definition
| Reversibly binding, alpha-1 and alpha-2 antagonist. |
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Term
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Definition
| Selective antagonist for Alpha-1 (allows alpha-2 feedback, prevents tachycardia from overstimulation with NE) |
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Term
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Definition
| selective Alpha-1 antagonist, used to treat benign prostatic hyperplasia (urinary retention) |
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Term
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Definition
| selective Alpha-1 antagonist, used to treat benign prostatic hyperplasia (urinary retention) |
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Term
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Definition
| Competitive antagonist for Beta-1 and Beta-2 |
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Term
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Definition
| long acting β1- and β2 antagonist |
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Term
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Definition
| β1- and β2 antagonist. Used to treat glaucoma |
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Term
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Definition
| Beta-2 antagonist, only modest B-1 antagonism (less effect on heart) |
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Term
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Definition
| Beta-1 and Beta-2 antagonist, with Alpha-1 blocking. Used for hypertensive emergencies. |
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Term
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Definition
| Beta-1 and Beta-2 antagonist, also Alpha-1 blocker. |
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Term
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Definition
| Selective Beta-1 antagonist (less likely to cause airway resistance, cause hypertension or delay recovery from hypoglycemia) |
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Term
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Definition
| Selective Beta-1 antagonist with a very short half life |
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Term
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Definition
| Indirectly reduces SNS activity. Inexpensive, used to treat moderate hypertension. |
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Term
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Definition
| Interferes with central SNS outflow, stimulate CNS Alpha-2 receptors |
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Term
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Definition
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Term
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Definition
| Centrally active Alpha-2 agonist (blocks central SNS tone). Eases drug withdrawl symptoms. |
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Term
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Definition
| MAO inhibitor, for mental depression (avoid giving Tyramine) |
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Term
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Definition
| Topical Beta antagonist (for glaucoma) |
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Term
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Definition
| Epi analogue, alpha antagonist. Reduces aqueous humor production |
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Term
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Definition
| Alpha-2 agonist (reduces aqueous humor production, for glaucoma) |
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Term
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Definition
| Carbonic anhydrase inhibitor (for glaucoma) |
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Term
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Definition
| Reverses 'irreversible AChE inhibitors' such as organophosphates, when used quickly |
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Term
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Definition
| Short duraction AChE inhibitor (reversible) |
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Term
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Definition
| lipid soluble AChE inhibitor (reversible, carbamate inhibitor), acts in CNS |
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Term
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Definition
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Term
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Definition
| Carbamate AChE inhibitor, insecticide used for head lice |
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Term
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Definition
| longer lasting carbamate AChE inhibitor |
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Term
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Definition
| AChE inhibitor, works in CNS to delay Alzheimer's disease |
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Term
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Definition
| Irreversible AChE inhibitor-> causes miosis |
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Term
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Definition
| Irreversible AChE inhibitor, insecticide |
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Term
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Definition
| Irreversible AChE inhibitor, agricultural insecticide (no longer used) |
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Term
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Definition
| Irreversible AChE inhibitor (bronchoconstriction, bradycardia, anhidrosios, miosis, salivation, lacrimation, defecation, urination) |
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Term
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Definition
| Muscarinic antagonist- more active in CNS than atropine, used for motion sickness |
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Term
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Definition
| muscarinic antagonist, used as aerosol to relax lungs in ppl with COPD |
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Term
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Definition
| muscarinic antagonist, used to relax lungs of ppl with COPD |
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Term
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Definition
| Muscarinic antagonist, causes mydriasis for eye exams |
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Term
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Definition
| Muscarinic antagonist, used to treat Parkansonian dyskinesia |
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Term
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Definition
| Muscarinic antagonist- relief from overactive bladder |
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Term
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Definition
| Nicotinic muscle antagonist, causes muscle weakness in a cephalad-caudad fashion, also bronchoconstriction |
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Term
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Definition
| Short acting Nicotinic muscle (Nm) antagonist |
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Term
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Definition
| Valium- GABAa agonist, relief from anxiety, muscle spasms. Sedative |
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Term
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Definition
| GABAb agonist, less sedative than diazepam |
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Term
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Definition
| Muscle relaxant, less sedative than Diazepam or Baclofen |
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Term
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Definition
| COMT inhibitor, used to treat Parkinson's disease |
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