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Autonomic Nervous System
ANS Francis-Davis
31
Medical
Professional
08/31/2011

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Term
What is an example of dual innervation that have th same overall effect?
Definition
Salivation/both divisions increase salivary secretion/ different types of saliva are produced Parasympathetic- has a dominant role, watery Sympathetic-thicker saliva/feeling of dry mouth
Term
Coordination and Cooperative effect
Definition
when two divisions act on different effectors to produce a unified effect
Term
Examples of coordinate or cooperative effects
Definition
Cooperation is best seen in control of the external genitalia
sympathetic activity causes ejaculation in males and reflex peristalsis in females
parasympathetic activity causes vasodilation and is responsible for erection of the penis and clitoris
Both are responsible for sexual response.
Term
Tissue that only have sympathetic innervation
Definition
the adrenal medulla, sweat glands, vascular smooth muscle, piloerector muscles of the skin, liver, adipose tissue and kidney
Term
What does the sympathetic division control without dual innervation?
Definition
The sympathetic division independently controls:
Thermoregulatory responses to heat
Release of renin from the kidneys
Metabolic effects
Term
What is the main intergration site of ANS activity and what does it control?
Definition
hypothalamus/ hunger, thirst, temperature regulation
Term
What does to midbrain, pons, and medulla oblongata control
Definition
nuclei for cardiac and vasomotor control, salivation, swallowing, sweating, bladder control, and pupillary changes
Term
What does the spinal cord relex control and how?
Definition
defecation and micturition reflexes are integrated in spinal cord

we control these functions because of our control over skeletal muscle sphincters
Term
What are the 2 NT of the ANS
Definition
ACh or NE
Term
What is the key to understanding the sffects of the ANS?
Definition
knowing which neurotransmitter it releases and what kind of receptors occur on the target cells.
Term
type of NT and receptor for parasypatheitc activity
Definition
preganglionic and postganglionic axons release acetylcholine and thus are called cholinergic
Term
THe type of NT and receptor produced by the sympathetic system
Definition
preganglionic axon and a few postganglionic axons in the are also cholinergic (sweat glands)
most postganglionic axons release norepinephrine and are called adrenergic
Term
Adrenal Medulla and the sympathetic nervous system
Definition
Preganglionic fibers that synapse on chromaffin cells of the adrenal medulla secrete acetylcholine

Upon stimulation, chromaffin cells secrete epinephrine (80%) and norepinephrine (20%) into the circulation.
Its a modified post sympathetic ganglion
Term
What is Pheochromocytoma
Definition
An adrenal tumor of the chromaffin cells. It causes excessive secretion of epinephrine and norepinephrine
Unlike normal adrenal it primarily secretes NE

Symptoms
Mimic the effects of sympathetic stimulation (i.e. increased HR, BP, cold hands and feet, etc.)
Term
What is the fate of NE?
Definition
Reabsorbed by nerve fiber and either reused or broken down by the enzyme monoamine oxidase (MAO)

Diffuse into the surrounding tissues, where it is degraded by another enzyme called catechol-O-methyltransferase (COMT)

Travel through bloodstream, where MAO and COMT are absent, then circulates throughout the body to exert synergistic effect with epinephrine from the adrenal gland

- Thus sympathetic effects tend to last longer than parasympathetic effects
Term
The type of receptors are found on the effect organs of the parasympathetic divison
Definition
muscarinic
Term
What type tissues does the ANS contorl and what are the primary effectors?
Definition
Controls glands, cardiac muscle, and smooth muscle Primary/effectors of the ANS viscera of thoracic and abdominal cavities body wall structures cutaneous blood vessels sweat glands piloerector muscles Not required for the effector function inly adjusts the activity
Term
WHat are the physiologic effects of the sympathetic nervous system?
Definition
Prepares body for physical activity (fight or flight)
Increases heart rate and blood flow
Deep and rapid breathing
The skin is cold (reduced blood flow) and sweaty
Dry mouth
Increases blood glucose
Inhibits digestive and urinary function
Term
the enzyme found in the chromaffin cell of the adrenal medulla that methylates epinephrine producing norepinephrine
Definition
phenyl-ethanolamine N-methyl-transferase (PNMT)
Term
What does the paravertebral ganglia in the body wall control
Definition
physiological effects above the liver (heart, eyes, saliva, bronchi)
Term
What are the physiologic effects of the parasympathetic nervous system?
Definition
Involves the D activities
digestion, diuresis and defecation
Keeps body energy use low
Its activity is illustrated in a person who relaxes after a meal
Blood pressure, heart rate, and respiratory rates are low
GI tract activity is high
The skin is warm and the pupils are constricted
Term
What does the prevertebral ganglia in the body wall control
Definition
anything below the liver (liver, stomach, bladder, intestine, and sexual organs)
Term
What tissues does the parasympathic system not innervate?
Definition
sweat glands, piloerector muscles, or cutaneous blood vessels
Term
How is autonomic tone produced?
Definition
Both systems acting simultaneously on the same target organ
Term
What is reciprocal or antagonistic effects of the ANS
Definition
when an organ has duel innervation and the effects oppose each other.
THis innervation can be on the same effector cells (heart)
different effector cells (the pupils of the eye)
Term
Does the parasympathetic system control contractility?
Definition
No, because it does not innervates the ventricles (only the SA, AV, and the atria)
Term
What occurs when the sympathetic predominates in the urinary bladder?
Definition
Filling
Detrusor Muscle Relaxes (beta 2)
Internal Sphincter Muscle Contracts (Alpha 1, skeletal, voluntary)

External Sphincter Muscle
Simultaneously Contracts Voluntarily
Term
What occurs when parasympathetic system predominates in the urinary bladder?
Definition
Emptying
Detrusor Muscle Contracts

Internal Sphincter Muscle Relaxes

External Sphincter Muscle
Simultaneously Relaxes Voluntarily
Term
What occurs when the sympathetic system predominates in the smooth muscle of the iris?
Definition
Pupillary dilator- radial muscle
Term
What occurs when the parasympathetic system predominates in the smooth muscle of the iris?
Definition
Pupillary constrictor –sphincter muscle
Term
WHat is an example of dual ANS regulation that is not antagonistic?
Definition
Salivation
both increase salivary secretions
Parasympathetic predominates and the saliva is watery
sympathetic causes a thicker mucus, causes dry mouth
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