Term
| What are the three atypical pneumonias? |
|
Definition
legionella (can also be lobar)
mycoplasma
chlamydia |
|
|
Term
| What is the most common serotype of legionella? |
|
Definition
|
|
Term
| What is the gram stain of legionella? |
|
Definition
|
|
Term
| What is the source of infection for legionella? |
|
Definition
| the environment (NOT HUMAN) |
|
|
Term
| What are the two ways of legionella transmission? |
|
Definition
|
|
Term
| What type of immunity responds to legionella and why? |
|
Definition
| cell-mediated because it is an intracellular bacteria |
|
|
Term
| Where is legionella found in the alveolar spaces? |
|
Definition
|
|
Term
| Where in the lung does legionella do its damage? |
|
Definition
| in the bronchioles and alveoli |
|
|
Term
| What is pontiac fever and what bacteria causes it? |
|
Definition
Pontiac fever is mild influenza with fever, chills, malaise, headace
it occurs in legionella infection |
|
|
Term
| If you have a patient with an atypical pneumonia that is not showing up on gram stain but with many WBC, what bacteria should come to mind? |
|
Definition
|
|
Term
| If a patient is not responding to conventional antibiotic in conjuction with cultures not revealing a pathogen, what should be considered? |
|
Definition
|
|
Term
| Why might legionella not grow on cultures when you ask for them in the lab? |
|
Definition
| becuase it has specific growth requirements, Buffered charcoal yeast extract |
|
|
Term
| What culture medium does legionella require? |
|
Definition
| bufffered charcoal yeast extract |
|
|
Term
| What is the gold standard for detecting legionella? |
|
Definition
| buffered charcoal yeast extract culture |
|
|
Term
| What is the disadvantage to doing direct flurorescent antibody testing of legionella? |
|
Definition
| it is serogroup dependent so you would have to do it 15 times |
|
|
Term
| What two bacterias have urine antigen tests? |
|
Definition
| legionella and Pneumococcus |
|
|
Term
| What is the disadvantage to legionella urine antigen test? |
|
Definition
| it only detects serogroup 1 |
|
|
Term
| What is the advantage to urine antigen test for legionella? |
|
Definition
| for small community lab that does not have ability to do charcoal yeast extract culture, it can at least verify legionella if suspected. CANNOT r/o legionella becuase it only detects serotype 1 |
|
|
Term
| What two general categories of drugs treat legionella? (think classes that treat atypical) |
|
Definition
|
|
Term
| What is true of mycoplasma pneumoniae cell wall? |
|
Definition
| trick question: it doesn't have one |
|
|
Term
How many antigens are there to mycoplasma?
|
|
Definition
|
|
Term
| What atypical pneumonia has P1 antigen that mediates attachment? |
|
Definition
|
|
Term
| What was mycoplasma once called by the lay person and why? |
|
Definition
| walking pneumonia b/c it is slow growing and not that severe |
|
|
Term
| What makes mycoplasma not as severe as other forms of pneumonia? |
|
Definition
|
|
Term
| Where do you see the majority of mycoplasma outbreaks? |
|
Definition
| military recruits and prisons |
|
|
Term
| What drug can you definately not give to mycoplasma pneumonia patients? |
|
Definition
| PCN because it has no cell wall |
|
|
Term
| What type of otitis media occurs in mycoplama pneumonia? |
|
Definition
|
|
Term
| How is mycoplasm diagnosised? |
|
Definition
|
|
Term
| Why are chlamydia organisms intracellular? WHat cant they make? |
|
Definition
| becuase they cannot make their own ATP |
|
|
Term
| What bacteria is known as bridge organisms? |
|
Definition
|
|
Term
What are the two bodies in the life cycle of chlamydia?
What are they each invovled in? |
|
Definition
elementary bodies-entry into cell (extracellular)
reticular bodies-replication |
|
|
Term
| What is the gold standard test in diagnosis of chlamydia? |
|
Definition
|
|
Term
| What is the problem with culture of chlamydia? |
|
Definition
|
|
Term
| What is usually done to diagnosis chlamydia? |
|
Definition
| nucleic acid amplification |
|
|
Term
| What are the serotypes involved in trachoma in chlamydia trachomatis? |
|
Definition
|
|
Term
| What does C. Trachomatis cause? |
|
Definition
keratoconjunctivitis
lymphogranuloma venereum
urethritis, cervicitis, PID epididymitis
Pneumonitis in newborns
|
|
|
Term
| What respiratory disease does C. Trachomatis cause? |
|
Definition
| cauases pneumonitis in newborns when he/she passes through birth canal |
|
|
Term
| What is the serotype for Chlamydia pneumoniae? |
|
Definition
|
|
Term
| What other bacteria is most like C. Pneumoniae in comparison to its clincial course? |
|
Definition
|
|
Term
| What is Chlamydia psittaci associated with? |
|
Definition
|
|
Term
| What is the patogenesis of C. psittaci? |
|
Definition
|
|
