Term
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Definition
Brand Name: Atrovent & Apovent
Clinical uses: Asthma and COPD
MOA: Anticholinergic (Antagonist at muscarinic receptors, especially M3,
Adverse Effects: Dry mouth, dry nasal mucus, constipation, tachycardia, paralytic ileus, angiodema, bronchospasm, abnormal taste |
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Term
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Definition
Brand Name: Spiriva
Clinical uses: Asthma and COPD
MOA: Anticholinergic (Antagonist at muscarinic receptors, especially M3,
Adverse Effects: Dry mouth, dry nasal mucus, constipation, tachycardia, paralytic ileus, angiodema, bronchospasm, abnormal taste |
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Term
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Definition
Brand name: N/A
Clinical Use: Asthma
MOA: non-selective adrenergic agonist
Adverse Effects: Cardiac arrhythmias, tachycardia, palpitations, sweating, nervousness, dypsnea |
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Term
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Definition
Brand: Isuprol
MOA: Beta adregnergic receptor agonist that stimulates Gs
AE: Tachyarrhythmias, restlessness, tremor
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Term
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Definition
Brand: Xopenex
MOA: S enantiomer of albuterol (salbutamol) and is more potent and selective compared to the racemic mixture of albuterol |
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Term
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Definition
Generic: Budesonide and Formoterol
MOA: Anti-inflammatory with long acting broncho-dilator
Dose: 1-2 puffs bid |
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Term
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Definition
Generic: Fluticasone and Salmeterol
MOA: Anti-inflammatory (Corticosteroid) with long acting broncho-dilator
Dose: 1 puff bid |
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Term
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Definition
Brand: Flovent
MOA: Corticosteroid (Prevent phosholipid release which causes an anti-inflammatory affect) |
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Term
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Definition
Generic: Albuterol and Ipratropium Bromide
MOA: Bronchodilation
Dose: 2 puffs qid |
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Term
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Definition
| MOA: Methylxanthine (Nonselective phosphodiesterase inhibitor that prevents the degradation of camp). Also is an adenosine receptor antagonist which has anti-inflammatory affect |
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Term
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Definition
Brand: Rhinocort (Nasal), Pulmicort (Oral), Entocort (sustained release capsule)
MOA: Corticosteroid (Prevents the release of phospholipids which causes anit-inflammation as a result) |
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Definition
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Term
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Definition
Brand: Asmanex
MOA: Corticosteroid |
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Term
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Definition
MOA: Inhibits chloride ion transport which affects calcium gating that prevents mediator release.
-Anti-inflammatory that prevents the release of mediators to inflammatory cells which in turn decreases the activity of inflammatory cells.
-Does not relieve an allergic response once it has happened |
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Term
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Definition
Brand: Zyflo
MOA: Leukotriene Pathway Modifying Agent that Inhibits 5-lipoxygenase |
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Term
| Montelukast and Zafirlukast |
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Definition
Brand: Montelukast (Singulair) & Zafirlukast (Accolate)
MOA: Leukotriene receptor antagonist |
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Term
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Definition
Brand: Xolair
MOA: Human monoclonal antibody that binds to the Ig-E which won't allow the Ig-E to attach to the Ig-E binding site on the mast cell |
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