Singulair

5-10 mg/day

-4 or 5 mg chewable tab

-4mg granule packet

-10mg tablets

Oral candidasis --> rinse mouth Hoarseness

1st line for persistant asthma not PRN

-tremor

-tachycardia

-prolonged QT interval (overdose)

-NOT for SOLE treatment

-hepatoxicity (1st 3 months)

-monitor LFTs at baseline

-headache

-GI upset

-interactions w/ Warfarin and theophylline

-injection site reactions

-urticaria

-thrombocytopenia

-anaphylaxis

-malignancy

-helpful in moderate-severe persistant asthma

-2nd line therapy

-very expensive

-bad taste

-cough

-takes ~ 2 weeks for onset

4-8 weeks for expected effects

-not for rapid relief

-N/V

-Headache

-nervousness

-tremors

-insomnia

-arrhythmias

-seizures

-serum levels: 5-15 mcg/mL

-not for acute relief

-check for drug interactions

-tachycardia

-tremor

-headache

-overuse:

- hypokalemia

- hyperglycemia

- lactic acid build up

-drug of choice for acute bronchospasms "quick relief"

-regular use indicates poor control

>2 canisters a month

>2 days a week

>1 inhaler relief per month

-dry mouth

-decreased respiratory secretions

-headache

-blurred vision

-ipratropium = COPD drug of choice

Spiriva = long acting, not for rapid relief