Term
iris - radial muscle contraction
receptor |
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Definition
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Term
cardiac stimulation
receptor |
|
Definition
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Term
vasoconstriction of vessels
receptor |
|
Definition
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Term
decreased GI motility
receptor |
|
Definition
alpha 1 and 2
beta 1 and 2 |
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Term
contraction of GI sphincters
receptor |
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Definition
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Term
bladder sphincter contraction
receptor |
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Definition
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Term
inhibition of insulin release
receptor |
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Definition
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Term
inhibition of lipolysis in adipose
receptor |
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Definition
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Term
adipose FA mobilization
receptor |
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Definition
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|
Term
increased Renin release
receptor |
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Definition
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Term
dilation of blood vessels; relaxation
receptor |
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Definition
beta 2
D1 in renal and mesentary |
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Term
receptor group causing generally relaxation of SM
receptor |
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Definition
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|
Term
increased insulin secretion
receptor |
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Definition
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Term
inc glycogenolysis and gluconeogenesis
liver and muscle
receptor |
|
Definition
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|
Term
increased glucagon secretion
receptor |
|
Definition
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|
Term
relaxation of bronchial SM
receptor |
|
Definition
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|
Term
relaxation of bladder detrussor muscle
receptor |
|
Definition
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|
Term
relaxation of uterus
receptor |
|
Definition
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|
Term
inhibition of norepi
receptor |
|
Definition
pre-synaptic alpha 2
pre-synaptic D2 |
|
|
Term
inhibiiton of ACH release
receptor |
|
Definition
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|
Term
inhibition of serotonin release
receptor |
|
Definition
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|
Term
increase norepi release
receptor |
|
Definition
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|
Term
natriuresis and diuresis
receptor |
|
Definition
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|
Term
stimulation of PTH release
receptor |
|
Definition
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|
Term
inhibition of prolactin release
receptor |
|
Definition
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|
Term
inhibition of dopamine release
receptor |
|
Definition
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|
Term
|
Definition
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Term
|
Definition
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Term
|
Definition
| blocks tyrosine hydroxylase |
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Term
|
Definition
blocks DOPA decarbosylase in periphory = more DOPA for conversion to dopamine in brain
used to treat Parkinsons |
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Term
|
Definition
blocks DA hydroxylase and acetaldehyde dehydrogenase;
decreases norepi, more importantly it causes buildup of acetaldehyde for alcohol treatment |
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Term
|
Definition
COMT inhibitor;
treatment of Parkinsons |
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Term
|
Definition
inhibits DA and NE movement into synaptic vesicles; DEC EPI, NE, AND DA
tx HTN and psychosis; |
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|
Term
| Reserpine contraindications |
|
Definition
| depression and peptic ulcers |
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|
Term
|
Definition
inhibits reuptake action of amine pump on NE, epi, DA, GABA, and serotonin;
tx depression, local anesthesia |
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Term
|
Definition
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Term
|
Definition
block the amine pump on presynaptic terminal;
tx depression |
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Term
|
Definition
block the amine pump on presynaptic terminal;
tx depression |
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|
Term
|
Definition
| inhibis NE by being taken up by alpha 2 to dec NE production; acts centrally on RLVM to tx HTN; peripherally it acts as a competitve inhibitor of DOPA decarboxylase |
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|
Term
|
Definition
prodrug of epi and norepi that can cross the BBB;
Tx Familial Dysautonomia |
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|
Term
|
Definition
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|
Term
|
Definition
| inhibition of transmitter exocytosis by cleavage of synaptobrevin etc |
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|
Term
|
Definition
MAO-A AND MAO-B inhibition;
tx depression and panic disorders |
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|
Term
|
Definition
MAO-A AND MAO-B inhibition;
tx depression and panic disorders |
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|
Term
|
Definition
inhibits MAO-B;
tx Parkinsons |
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|
Term
|
Definition
alpha- 1 and 2
beta-1 NOT2 |
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|
Term
|
Definition
| alpha-1 agonist; vasoconstriction, increased BP |
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|
Term
|
Definition
| alpha-1 agonist; decongestant (vasoconstriction of nasal mucosa) |
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|
Term
|
Definition
alpha-2 agonist;
sedative, anti-anxiety |
|
|
Term
|
Definition
| beta-1 and 2 agonist; decrease TPR, decrease MAP, but increase HR |
|
|
Term
|
Definition
alpha-2 agonist;
works in RVLM to decrease BP;
sedative, anti-anxiety |
|
|
Term
|
Definition
beta-1 agonist to inc HR;
at high doses... beta-2 and alpha-1 also |
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|
Term
|
Definition
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|
Term
|
Definition
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|
Term
|
Definition
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|
Term
|
Definition
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|
Term
|
Definition
|
|
Term
|
Definition
| beta-2 agonist, long-acting |
|
|
Term
|
Definition
| beta-2 agonist, long-acting |
|
|
Term
|
Definition
| beta-2 agonist; prevents premature labor |
|
|
Term
| contraindications of sympathomimetics (4) |
|
Definition
hyperthyroidism;
heart disease;
severe hypertension;
inhalation anesthesia |
|
|
Term
indirect sympathomimetics
mechanism |
|
Definition
| work pre-synaptically on NT release |
|
|
Term
|
Definition
taken up by amine pump to increase NT secretion: NE, DA, serotonin;
tx psychogenic disorders, narcolepsy;
effects on alpha and beta |
|
|
Term
|
Definition
taken up by amine pump, inc secretion of NE;
alpha and beta effects |
|
|
Term
|
Definition
| direct agonist on alpha-1 and beta-2; indirect by inc release of NE (+alpha-2, beta-1); tx narcolepsy |
|
|
Term
|
Definition
direct on alpha-1;
indirect by increasing NE (+alpha-2, beta-1);
tx hypotension |
|
|
Term
|
Definition
taken up by amine pump to increase NT secretion: NE, DA, serotonin;
tx psychogenic disorders, narcolepsy;
effects on alpha and beta |
|
|
Term
|
Definition
taken up by amine pump to increase NT secretion: NE, DA, serotonin;
tx psychogenic disorders, narcolepsy;
effects on alpha and beta |
|
|
Term
| alpha antagonist contraindications (3) |
|
Definition
| hypotension; heart disease; peptic ulcer |
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|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| beta antagonist contraindications (6) |
|
Definition
severe CHF;
AV heart block;
Diabetics on Insulin;
Peripheral Vascular Dz;
Renal Insufficiency;
Bronchial asthma |
|
|
Term
|
Definition
beta-1 antagonist;
partial agonist |
|
|
Term
|
Definition
|
|
Term
|
Definition
Beta-1 and 2 + alpha-1 antagonist;
tx HTN |
|
|
Term
|
Definition
Beta-1 and 2 + alpha-1 antagonist;
tx HTN |
|
|
Term
|
Definition
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|
Term
|
Definition
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|
Term
|
Definition
beta-1 antagonist;
causes a release of NO |
|
|
Term
|
Definition
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|
Term
|
Definition
Beta-1 and 2 antagonist; direct effect on Na channels, prevents arrythmias
Partial agonist |
|
|
Term
|
Definition
Beta-1 and 2 antagonist;
direct effect on Na channels, prevents arrythmias |
|
|
Term
|
Definition
beta-1 and 2 antagonist;
tx glaucoma, migraines |
|
|
Term
| contraindications of beta antagonists (6) |
|
Definition
CHF;
AV block;
diabetics on insulin;
peripheral vascular dz;
renal insufficiency;
bronchial asthma |
|
|
Term
|
Definition
D1 and D2 agonist (non-selective);
tx Parkinsons |
|
|
Term
|
Definition
|
|
Term
|
Definition
D1 agonist;
promotes diuresis and natriuresis to lower BP |
|
|
Term
|
Definition
D2 agonist;
inhibit prolactin release;
tx Parkinsons and impotency |
|
|
Term
|
Definition
D1 and D2 antagonist;
tx psycogenic disorders |
|
|
Term
|
Definition
|
|
Term
|
Definition
alpha 1 agonist (indirect);
tx of narcolepsy |
|
|
Term
|
Definition
|
|
Term
|
Definition
COMT inhibitor;
tx Parkinsonism |
|
|
Term
|
Definition
beta 1 antagonist;
antiarrthymic |
|
|
Term
|
Definition
beta 1 and 2 antagonist;
antiarrthymic |
|
|
Term
|
Definition
|
|
Term
|
Definition
inhibition of NE release (after transient increase of NE);
tx ventricular arrhythmias |
|
|
Term
|
Definition
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|
