Term
| Discovered human blood groups in 1900 |
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Definition
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Term
| Most common cause of ABO discrepancies (excluding clerical error) |
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Definition
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Term
| An RBC suspension used for forward grouping that is TOO CONCENTRATED will cause false...(negative/positive)? |
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Definition
| false negative due to antigen excess |
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Term
| Insufficient washing of red cells in DAT testing will result in a false... (negative/positive)? |
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Definition
| False negative due to traces of unbound globulin which neutralize the AHG reagent |
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Term
| Approximate % of Group O individuals in the US |
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Definition
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Term
| Saline containing colloidal silica will have what effect on Coomb's testing? |
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Definition
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Term
| ABO antibodies may be of what immunoglobulin class? |
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Definition
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Term
| List the blood groups in irder of decreasing H substance |
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Definition
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Term
| Describe how the use of EDTA plasma prevents activation of complement by the classical pathway. |
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Definition
| EDTA chelates Ca2+ ions which prevents the assembly of C1 |
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Term
| A 24 yo A neg female was transfused with 65cc or A pos RBCs. How many doses of RhIg should she receive? |
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Definition
| 5 doses; 1 dose of RhIg conteracts approx 15mL RBC, plus 1 extra dose (policy may vary depending on hospital) |
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Term
| A pregnant A neg patient suffers a feto-maternal hemorrhage of 65cc. How many doses of RhIg should she receive? |
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Definition
| 3; a dose or RhIg conteracts approx 30mL fetal bleed, plus 1 extra dose (policy may vary depending on hospital) |
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Term
| The only blood component containing both VonWillebrands Factor and Factor VIII |
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Definition
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Term
| What would be the transfusion component of choice for a bleeding patient with a prolonged bleeding time, increased PTT, decreased levels of Factor VIII antigen, and impaired platelet aggregation with ristocetin? |
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Definition
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Term
| How many units of platelet concentrates would be needed to raise the platelet count by 150,000/mm3 in an average sized adult? |
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Definition
| minimum of 15, maximum of 30; one dose of platelet concentrate raises the platelet count by about 5,000-10,000/mm3 |
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Term
| A patient has experienced febrile reactions following 2 RBC transfusions. What would be the best component to use if subsequent transfusions are needed? |
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Definition
| Leukoreduced RBCs; most febrile nonhemolytic reactions are due to cytokines released from WBCs in stored blood |
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Term
| State the criteria for blood donors (age, oral temp, BP, Hct/Hgb, pulse, weight) |
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Definition
Age >16yrs
Temp: <=37.5C or 99.5F
BP <=180 systolic, <=100 diastolic
Hct >=38%, Hbg >=12.5
Pulse 50-100 beats/min
Weight >=110lbs |
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Term
| Expiration for ACD/CPD/CPD2 anticoagulated red cells |
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Definition
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Term
| Expiration for CPDA-1 anticoagulated red cells |
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Definition
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Term
| Expiration for packed red cells containing additive solution (AS-1, AS-3, AS-5) |
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Definition
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Term
| State the calculation for determining volume or red cells to draw based on weight. |
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Definition
| (donor weight(lbs)/110)*450 (if weight is given in kg, divide by 50 instead of 110) |
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Term
| State the calculation for determining amount of anticoagulent to add to donor RBCs of <300mL |
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Definition
| volume RBCs*0.14 (14%) (subtract from 63 to determine how much anticoagulent to remove from primary bag prior to draw) |
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