| Term 
 
        | "caines" with one "i"s cocaine, benzocaine, procaine, propoxycaine, tetracaine
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | "caines" with two "i"s lidocaine, mepivacaine, bupivacaine, ropivacaine, etidocaine, prilocaine
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | norepinephrine, epinephrine, phenylephrine, felypressin |  | Definition 
 
        | vasoconstrictors adjunct to local anesthetics to prolong duration |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Most superficial afferent neurons block |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | in the muscle, blocks more neurons thatn surface |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Blocks nerve trunks and not just individual nerves |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | self explanatory, blocks everything below where the anesthesia is injected in the spine |  | 
        |  | 
        
        | Term 
 
        | Type A Nerve fiber Type alpha Nerve Fiber
 |  | Definition 
 
        | Motor, proprioception. Biggest diameter >12. Least sensitive to block, fastest conduction. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Touch and pressure, 5-12 diameter |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Muscle Spindles 3-6 micrometer diameter |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Pain, Temperature 1-4 diameter. Slowest conduction but highest sensitivity AMONG TYPE A NERVE FIBERS |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Prganglion, sympathetic. Lower than 3 diameter. |  | 
        |  | 
        
        | Term 
 
        | Type C; Dorsal Root sympathetic |  | Definition 
 
        | Pain (0.4-1.2), Postganglionic sympathetic. (0.3-1.3 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Used as a preservative for local anesthetics. Reason why some anesthetics caused allergic reactions |  | 
        |  | 
        
        | Term 
 
        | Atypical Pseudocholinesterase |  | Definition 
 
        | A genetic variation of an enzyme |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Prilocaine, lidocaine, benzocaine metabolites can cause this |  | 
        |  | 
        
        | Term 
 
        | General Anesthesia Induction |  | Definition 
 
        | Time it takes to achieve surgical anesthesia |  | 
        |  | 
        
        | Term 
 
        | General Anesthesia Maintenance |  | Definition 
 
        | Keeping patient at stable state of surgical anesthesia |  | 
        |  | 
        
        | Term 
 
        | General Anesthesia Emergence |  | Definition 
 
        | Recovery from general anesthesia |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Might still feel pain but brain cant tell wherer its coming from. Patient awake and consicous |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Inhibits inhibitory mechanism first causing respiration, BP, HR to increase and muscles to twitch |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | The stage where you want to maintain the patient |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Too much anesthetic can cause death |  | 
        |  | 
        
        | Term 
 
        | MAC or minimum alveolar concentratoin |  | Definition 
 
        | Amount of gas that knocks out 50% of the patient |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Combination of drag that adds up to full mac value |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | General anestehtic inhalation agents |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Fluorinated hydrocarbon as general anesthetic inhalation agent |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Fluorinated hydrocarbon as general anesthetic inhalation agent |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Fluorinated hydrocarbon as general anesthetic inhalation agent |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Only effective drug to interfere with excitation contraction complement |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | IV general anesthetic agent that enhance inhibitory GABA neurotransmission 	no analgesia or skeletal muscle relaxation (combine opioid)
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | IV general anesthetic agent that enhance inhibitory GABA neurotransmission 	no analgesia or skeletal muscle relaxation (combine opioid)
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | IV general anesthetic agent that enhance inhibitory GABA neurotransmission 	no analgesia or skeletal muscle relaxation (combine opioid)
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | IV general anesthetic agent that enhance inhibitory GABA neurotransmission. This is a benzodiazepine 	no analgesia or skeletal muscle relaxation (combine opioid)
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | IV general anesthetic agent that inhibit excitatory NMDA neurotransmission. Dissociate anesthsia with analgesia |  | 
        |  | 
        
        | Term 
 
        | droperidol/fentanyl (Innovar®) |  | Definition 
 
        | IV general anesthetic agent - neuroleptanalgesia (neuroleptic and analgesic drug) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Neurotransmitter released from pain signals |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Antidotal Therapy for morphine toxicity (short duration) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Antidotal Therapy for morphine toxicity (long acting) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Phenanthrenes, Opium alkaloids |  | 
        |  | 
        
        | Term 
 
        | Hydromorphone/codone: oxymorphone/codone - Diacetylmrphine |  | Definition 
 
        | Semisynthetic opiate drugs |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Phenylptylamines. 3x morphine potency |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Phenylptylamines - treatment of addiction |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | phenylpiperidines: 1/8 x morphine potency |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | phenylpiperidines: 80x morphine potency |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | phenylpiperidines: 10x morphine potencyt |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | phenylpiperidinesL 500x morphine potnecy |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | phenylpiperidines 8000x morphine opotency - for bears and big animals |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | endogenous opioid peptides - brain and spinal cord neurotransmitter; also releaed from adrenal medulla as a hormione. mu and delta receptors |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | endogenous opioid peptides, brain neurotransmitter and pituitary hormone. Mu and epsalon. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | endogenous opioid peptides . Brain and spinal cord neurtransmitter. exclusively kappa |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Brain neurotransmitter. Mu |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | for morphine and most clinical narcotic analgesics; thought to produce strongest analgesia |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | for mixed agonist-antagonist |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | agonist under development. better for neuropathetic pain. and less addiction etc. |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | Mixed antagonist(mu) - agonist(kappa). |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Mixed antagonist(mu) - agonist(kappa). |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Mixed antagonist(mu) - agonist(kappa). |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Ergot derived prophylactic agent for migraines. prevent initial 5HT induced vasoconstriction |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | nonspecific vascular smooth muscle stimulation to reverse reactive vasodilation |  | 
        |  | 
        
        | Term 
 
        | Sumatriptan, rizatriptan, eletriptan |  | Definition 
 
        | Stimulation of 5HT to promote vasoconstriction |  | 
        |  | 
        
        | Term 
 
        | Ascending Reticular activation system (ARAS) or reticular formation |  | Definition 
 
        | sends message to cortex from peripheral afferent neurons |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | A thiobarbiturate. Ultra short acting barbiturate sedative |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | short-to intermidiate acting oxybarbiturate |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | short-to intermidiate acting oxybarbiturate |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | short-to intermidiate acting oxybarbiturate |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | long-acting (oxy)barbiturate |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | long-acting (oxy)barbiturate : prodrug of phenobarbital |  | 
        |  | 
        
        | Term 
 
        | Ultrashort acting barbiturates |  | Definition 
 
        | Useful for IV general anesthetics |  | 
        |  | 
        
        | Term 
 
        | short-tointermediat acting barbiturates |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | long-acting anticonvulsants barbiturates |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | acute intermittent porphyria |  | Definition 
 
        | Only absolute contraindication of barbiturates. Porphyrins, which are needed for hemoglobin are created in excess and stored in tissues. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | antagonizes benzodiazepines and imidazopyridines |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | agonist at melatonin 1 and 2. no direct effect on gaba. only non scheduled rx to treat insomnia |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Centrally-Acting Muscle Rexalants -drugs that likely facilitate inhibitory GABAA neurotransmission |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Centrally-Acting Muscle Rexalants -drugs that likely facilitate inhibitory GABAA neurotransmission |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Centrally-Acting Muscle Rexalants -drugs that likely facilitate inhibitory GABAA neurotransmission |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Centrally-Acting Muscle Rexalants -drugs that likely facilitate inhibitory GABAA neurotransmission |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Centrally-Acting Muscle Rexalants -drugs that stimulate inhibitory GABAB receptors |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Centrally-Acting Muscle Rexalants - drugs that facilitate inhibitory 2 adrenergic neurotransmission |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Centrally-Acting Muscle Rexalants peripherally-acting muscle relaxant competitive antagonism of ryanodine receptor to interfere with calcium release and excitation-contraction coupling (ECC) in skeletal muscle
 |  | 
        |  | 
        
        | Term 
 
        | Rate limiting step of ethanol metabolism |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | 3xnormal rate of EtOH to acetaldehyde. 80% in asians |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | near inactive form or acetaldehyde dehydrogenase. 60% of asians |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | acetaldehyde dehydrogenase inhibitor. aversion therapy. |  | 
        |  | 
        
        | Term 
 
        | Greseofulvin, metronidazole, sulfonylureas. |  | Definition 
 
        | has signifianct disulfiram like action |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Circulatory, respiratory depression, coma, death |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Stupor, confused, unable to stay awake |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Depressed sensory and motor capability, difficulty staying awake, really slurred speech, double vision |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Impairment of balance, movement, judgment and perception; blurred vision; ataxia |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Slow reaction time, impaired motor function, slurred speech |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Lowered alertness, feeling of well-being |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Relaxation, happy, mild motor impairment |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | consciousness impaired and unresponsive |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | most common type of seizure. consciousness impaired; initial contraction of muscles (tonic phase) followed by rhythmic contractions (clonic phase) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Sudden brief herky jerky movements ofm uscles. no paralysis, no loss of awareness or consciousness. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Lose all muscle tone and just collapse. theres a disturbance in cosciousness as well. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Treatment of psychomotor and tonic-clonic epilepsies |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Treatment of psychomotor epilepsy |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Pro drug turns into pehnobarbital and phenlethylmalonamide. treatment of psychomotor epilepsy and psychomotor and tonic-clonic epilepsies |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | treatment of absence and myoclonic epilepsies |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | treatment of status epilepticus |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Treatment of psychomotor and tonic-clinc epilepsies. treatment of trigeminal and facial neuralgias |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Treatment of psychomotor, tonic-clonic absence of mycolonic epilepsies |  | 
        |  | 
        
        | Term 
 
        | Ethosuximide, Trimethadione |  | Definition 
 
        | Treatment of petitmal epilepsy |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Centrally acting GABA agonist |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Positive modulateor of GABA receptors |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Inhibitor of GABA reuptake |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | NA channel blocker but may also block voltage-activated Ca++ |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Inhibit spread of electrical activity by unknown mechanism |  | 
        |  |