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Aphasia lecture 3
Medical aspects of stroke and implications for rehabilitation
67
Other
Graduate
06/11/2010

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Term
Every 24 hours your brain needs _____ gm of glucose and ____ liters of oxygen.
Definition
150;72
Term
Aphasia
Definition
caused by malfunction of the language-competent regions of the brain.
Term
stroke
Definition
Most common cause of dysfunction. It is the interruption of the brain's blood supply.
Term
Cerebral vascular accident (CVA)
Definition
synonymous with the term, stroke. (Interruption of the brain's blood supply)
Term
apoplexy
Definition
Older term for "stroke"
Term
Stroke symptoms
Definition
(depends on area of the brain affected)
partial or complete loss of voluntary movement or sensation in a leg or arm; speech problems; weak facial muscles; numbness or tingling; balance;vision; swallowing; breathing difficulties; or unconsciousness.
Term
Etiology of stroke
Definition
hypertension, atherosclerosis, heart disease, infections, trauma, drugs, arterial dissection, cocaine, congenital absence or atresia of artery, radiation fibrosis, vasculitis, HIV, fibromuscular hyperplasia, moyamoya disease, hypertensive encephalopathy, sickle cell disease
Term
Acute events
Definition
Initial stage of pathologic condition, PROGRESSES RAPIDLY; symptoms FULLY DEVELOPED within minutes to a day or two. Immediately following the injury there is a generalized disruption of cerebral processes. Parts of the brain not directly injured cease to function or function poorly. There is a GENERALIZED disruption of brain function.
Term
Acute events
Definition
Initial stage of pathologic condition, PROGRESSES RAPIDLY; symptoms FULLY DEVELOPED within minutes to a day or two.
Term
insidious process
Definition
Progresses SLOWLY; symptoms develop in piecemeal fashion over months or years to be fully expressed.
Term
Acute events
Definition
Functions gradually resolve leaving more limited disruption of specific processes. Pattern of disruption depends on actual location of damage in the brain.
Term
Two major types of acute neurological events
Definition
cerebral ischemia, cerebral hemorrhage
Term
4 types of cerebral ischemia
Definition
Thrombosis, Embolism, Lacunar, transient Ischemic Attack (TIA)
Term
3 types of hemorrhage
Definition
Extracerebral, intracerbral, arteriovenous malformations
Term
Ischemic Strokes
Definition
account for more than 80% of strokes; AKA "occlusive stroke." Ischemia developes after 30 seconds of restriction. After 1 minute, neural function may cease. Blocked artery results in loss of blood supply to CNS tissues.
Term
Infarct
Definition
> 5 mintues, death of tissue caused by interruption of blood supply
Term
Necrosis
Definition
death of tissue
Term
Thrombotic
Definition
Gradual accumulation & plugging of artery until closed. Begins in area of slowed blood flow & increase turbulence. Occurs in LARGE arteries.
Term
Plug
Definition
Atherosclerotic plaque (fatty deposits & fibrous material) thickening over years. May form as a "clot" as blood platelets & fibrin adhere to arterial plaque area. If clot breaks off & floats, becomes embolic material.
Term
Embolic
Definition
Artery is occluded by a fragment of material that has traveled through the circulatory system until it reaches a blood vessel smaller than its own diameter, it stops, occluding the artery. Symptoms are sudden over a few minutes.
Term
Plaque
Definition
lining of artery, tumor tissue, bacteria, or other solids in the blood stream.
Term
Lucunar
Definition
small subcortical infarcts (<15mm diameter) in territory of deep penetrating arteries. (Basal ganglia, internal capsule, thalamus, corona radiata & pons). This is small vessel disease. The most common symptom is hemiparesis and the 2nd most common symptom is dysarthria.
Term
Transient Ischemic Attacks
Definition
(AKA: mini-stroke) a temporary disruption (focal) of cerebral circulation. Temporary physical & sensory symptoms lasting 2 to 30 minutes to up to 24 hours. it is a sign of potential impending major stroke.
Term
After a TIA ___% to ____% have a major stroke within 1 year.
Definition
10; 20
Term
After a TIA __% to ___% have a major stroke within 5 years.
Definition
30; 60
Term
cerebral hemorrhage
Definition
Caused by rupture of a cerebral blood vessel facilitated by weakness in vessel wall, trauma to vessel and/or extreme fluctuations in blood pressure.
Term
Extracerebral hemorrhage
Definition
Bleeding in the meninges or into surface spaces.
Term
Intracerebral hemorrhage
Definition
Bleeding within brain or brainstem. Common locations are in & around the thalamus, basal ganglia, brainstem (pons) & cerebellum. Usually associated with High BP. Most are not surgically manageable.
Term
Arteriovenous malformations
Definition
Swollen & distended veins connected to twisted mass of arteries. These can cause headache & other CNS symptoms; Walls may be weak, leading to leaking or rupture & subarachnoid hemorrhaging. If caught, it can be surgically treated.
Term
Cerebral Hemorrhage comprise ___% of CVAs
Definition
10
Term
Hematoma
Definition
Accumulation of blood secondary to a hemorrhage. Pools causing pressure & irritation to surrounding tissues.
Term
subdural hematoma
Definition
Hemorrhage into space beneath the dura and arachnoid layers of meninges.
Term
aneurysm
Definition
Ballooning or out pouching of weakened portion of arterial blood vessel. if it hemorrhages, it resuts in hematoma
Term
classifications of extracerebral hemorrhages are determined by ________
Definition
location
Term
subarachnoid hemorrhage
Definition
most common, caused by ruptured aneurysms; common places of occurrence: internal carotid, anterior cerebral artery & middle cerebral artery.
Term
Hypertension is present in ___% of cerebral hemorrhages
Definition
90
Term
Hypertension
Definition
leads to degenerative changes in small penetrating arteries, weakening walls & creating microaneurysms.
Term
Physiological changes after the stroke
Definition
after 2-4 weeks, swelling begins to recede; physical/cognitive behaviors begin to improve; cerebral blood flow to undamaged neurons is restored and neurotransmitters are reabsorbed.
Term
spontaneous recovery period
Definition
(30 days is generally accepted as the time frame for this)Although it is difficult to predict recovery until post-injury stability returns.
Term
Recovery for acute events
Definition
Ischemic & hemorrhagic strokes have different courses of recovery, and one must wait 3-4 weeks before predicting recovery.
Term
Recovery for acute events depends on what 2 things?
Definition
amount of brain tissue destroyed & location of destruction
Term
Recovery from Ischemic strokes
Definition
greatest recovery is in first weeks with gradual deceleration of rate. Recovery is greatest for patient in middle severity ranges.
Term
Severe vs mild Ischemic strokes (recovery)
Definition
Severe remain severe; mild attain premorbid levels
Term
Most recover from Ischemic strokes within ___months after onset.
Definition
3
Term
Recovery of Ischemic strokes is complete by ____ months after onset.
Definition
6
Term
Recovery of Hemorrhagic strokes
Definition
Usually little improvement in 1st 4-8 weeks, followed by period of rapid recovery, then slows & stablizes. Recovery is usually completed by 6 months after onset.
Term
Recovery of Hemorrhagic strokes
Definition
Usually little improvement in 1st 4-8 weeks, followed by period of rapid recovery, then slows & stablizes. Recovery is usually completed by 6 months after onset.
Term
Insidious processes
Definition
Presence known slowly, over a period of time rather than all at once. Difficult to determine time of onset. Pathology may be advanced when seen by physician for first time.
Term
Insidious processes may cause...
Definition
aphasia, dementia, dysarthria, and personality disruptions.
Term
Name 6 different insidious processes
Definition
Intracranial tumors, hydrocephalus, infections, toxicities, metabolic disorders, and nutritional
Term
2 types of gliomas
Definition
Astrocytomas, glioblastoma multiform
Term
Metastatic tumors
Definition
cancer that started elsewhere but spread to the brain via the bloodstream.
Term
What are two types of bacterial insidious brain infections?
Definition
meningitis, brain abcesses
Term
Toxicities that cause insidious processes
Definition
drugs, bacterial, heavy metals
Term
Name two metaboloic disorders that cause insidious processes
Definition
severe hypoglycemia & thyroid disorders
Term
T/F Most patients are seen by a physician before they are seen by an SLP.
Definition
True
Term
Neurologists want to determine...
Definition
Location & extent of pathology; location & extent of pathology; nature and cause of pathology; course of pathology-static, resolving, progressive.
Term
What are the 3 components of a medical diagnosis?
Definition
patient's medical history (most important), examination of the patient, tests
Term
6 areas of the examination
Definition
cranial nerves, motor system, sensory system, coordination and balance, visual fields, reflexes, cortical function
Term
4 types of medical tests
Definition
labs, carotid doppler study, cerebral angiography, brain imaging.
Term
carotid doppler study
Definition
ultrasound of carotid arteries for blockaages at bifurcation
Term
cerebral angiography
Definition
dye injected into arterial vessels to detect blockages
Term
Name 4 types of brain imaging
Definition
computed tomography (CT), Magnetic resonance Imaging (MRI), Positron Emission Computed tomography, Single photon Emission Computer Tomography
Term
MRI
Definition
contrasts gray from white matter very well; non-radiation study
Term
1st step in medical treatment of a stroke
Definition
Determine the type of stroke by using a CT scan or MRI. These help determine if it's a clot or a bleed, and the initial amount of potential damage to the brain.
Term
Tissue plasminogen Activator (t-PA)
Definition
used within 3 hours of an ischemic attack, known as a clot-buster (dissolves the clotted area); cannot be given to hemorrhage patients, patients with clotting problems, bleeding ulcers, very high blood pressure, or brain cancer. Aspirin and/or other antiplatelet medications cannot be taken with t-PA
Term
Treatment of Hemorrhagic CVA
Definition
Difficult to treat; efforts are made to control bleeding, reduce pressure in the brain & stablize viatal signs, especially blood pressure. Few meds available to stop bleeding, Meds given to reduce potential pressure on the brain; surgery may relieve blood collections or aneurysm, but not of mild to moderate bleeding.
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