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Ap Biology - DNA
Flashcards about DNA andDNA Replication
29
Biology
11th Grade
05/24/2012

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Term
DNA
Definition
Deoxyribonucleic Acid. A nucleic acid found in the nucleus that codes for herditable genetic information and is used to make proteins.
Term
Nucleic Acid
Definition
Polymers made of monomers called nucleotides.
Term
Nitrogenous Bases in DNA
Definition
Cytosine
Thymine
Adenine
Guanine
Term
Pyrimidines
Definition
One ring nitrogenous bases:
Cytosine
Thymine
Term
Purines
Definition
Two ring nitrogenous bases:
Adenine
Guanine
Term
Base Pairs
Definition
Adenine pairs with Thymine
Cytosine pairs with Guanine
Term
Nucleotide
Definition
One unit of a nucleic acid.
Term
Structure of a Nucleotide
Definition
Consists of a phosphate group, a pentose sugar, and a nitrogenous base. In DNA, the pentose sugar is called deoxyribose.
Term
DNA's Shape
Definition
A double helix. Similar to a twisted ladder.
Term
Antiparallel
Definition
The two sugar-phosphate DNA backbones run in opposite 5'-> 3' directions.
Term
DNA Replication
Definition
The process by which DNA is copied.
Term
Semiconservative Model
Definition
A model for DNA replication where one molecule of DNA gives rise to two new molecules. Each of the new molecules contains one strand from the original DNA. After a third replication, two molecules of DNA consist of the original DNA plus the brand new DNA, and two molecules consist of the new strand from the first replication as well as a brand new strand.
Term
Conservative and Dispersive Model
Definition
Two out of date models of DNA replication.
Term
Origin of Replication
Definition
Sites where DNA replication begins, which have a specific sequence of nucleotides.
Term
Replication Fork
Definition
A Y-shapes region where the parental strands of DNA are being unwound.
Term
Helicases
Definition
Enzymes that untwist the double helix at the replication forks, separating the two parental strands and making them available as template strands.
Term
Single-Strand Binding Proteins
Definition
Bind to the unpaired DNA strands, keeping them from re-pairing.
Term
Topoisomerase
Definition
Helps relieve the strain on the replication fork from untwisting the DNA. They break, swivel, and rejoin the DNA strands.
Term
Primase
Definition
An enzyme that synthesized RNA primers, using the parental DNA as a template.
Term
DNA Polymerases
Definition
Catalyze the synthesis of new DNA by adding nucleotides to a preexisting chain.
Term
Leading Strand
Definition
The strand running in the 5'-> 3' direction. Can be synthesized normally.
Term
Lagging Strand
Definition
The 3'-> 5' strand that must be synthesized with the help of Okazaki fragments.
Term
Okazaki Fragment
Definition
Segments of the lagging strand as it is being synthesized.
Term
DNA Ligase
Definition
Joins the sugar-phosphate backbones of all the Okazaki frgments into a continuous DNA strand.
Term
Mismatch Repair
Definition
When other enzymes remove and replace incorrectly paired nucleotides that hacve resulted from replication errors.
Term
Nuclease
Definition
A DNA-cutting enzyme.
Term
Telomeres
Definition
Special nucleotide sequences at the ends of DNA molecules. They do not contain genes and typically consist of multiple repetitions of one short nucleotide sequence. They protect genes from erosion.
Term
Telomerase
Definition
Catalyzes the lengthening of telomeres in eukaryotic germ cells.
Term
Chromatin
Definition
A complex of DNA and histone proteins.
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