Term
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Definition
| Chain terminates viral DNA, and the chain inactivates viral-DNA polymerase |
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Term
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Definition
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Definition
| Inhibits DNA polymerase but does not chain terminate |
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Definition
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Definition
| Inhibits Herpes simplex viral DNA synthesis |
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Term
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Definition
| Long chain saturated alcohol which inhibits fusion between plasma membrane and viral HSV envelope |
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Term
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Definition
| Chain terminates viral DNA, and the chain inactivates viral-DNA polymerase |
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Term
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Definition
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Term
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Definition
| Activated by intracellular phosphoyrlation and inhibits CMV DNA polymerase |
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Term
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Definition
| Pyrophosphate analog that inhibits viral DNA polymerase |
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Term
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Definition
| block uncoating of myxoviruses (Influenza A), via inhibition of hydrogen ion channels which normally allow the acidification and resultant uncoating of this virus |
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Term
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Definition
| Neuraminidase inhibitor; Bind neuraminidase |
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Term
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Definition
| Neuraminidase inhibitor; Bind neuraminidase |
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Term
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Definition
| Purine analog that inhibits Influenza A and B, and RSV, and somewhat Hep-C |
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Term
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Definition
| Monoclonal antibody used to prevent RSV in high-risk infants and children with respiratory disease |
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Term
| Nucleoside Reversie Transcriptase Inhibitors (MOA) |
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Definition
| activated by phosphorylation, cause chain termination and inhibit rev. transcriptase; combo therapy only |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| emtricitabine (MOA/class) |
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Definition
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Term
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Definition
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Term
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Definition
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Term
| Non-nucleoside Rev. Transcriptase Inhibitors (MOA) |
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Definition
| inhibit RT activity but are not nucleoside analogs; bind directly to RT and inhibit |
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Term
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Definition
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Term
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Definition
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Definition
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Definition
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Term
| Protease Inhibitors (MOA) |
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Definition
| bind to HIV aspartate protease active site and prevent enzyme from cleaving the protein precursors, thus blocking viral formation |
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Term
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Definition
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Term
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Definition
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Term
| atazanavir/ritonavir (MOA/class) |
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Definition
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Term
| lopinavir/ritonavir (MOA/class) |
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Definition
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Term
| fosamprenavir/ritonavir (MOA/class) |
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Definition
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Term
| darunavir/ritonavir (MOA/class) |
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Definition
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Term
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Definition
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Term
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Definition
| fusion inhibitor; interferes w/ HIV binding to host cell membrane via HIV gp41 |
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Term
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Definition
| CCR5 co-receptor antagonist; blocks HIV entry receptor CCR5 (that interacts with HIV gp120) |
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Term
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Definition
| integrase strand transfer inhibitor; inhibits final step in integration catalyzed by integrase |
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Term
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Definition
| integrase strand transfer inhibitor; inhibits final step in integration catalyzed by integrase |
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