Term
|
Definition
| Trifluridine, Vidarabine, Ribavirin, Idoxuridine, Acyclovir, Peniciclovir, Ganciclovir |
|
|
Term
| Preferentially phosphorylated to acyclo-GMP by viral thymidine kinase |
|
Definition
| Acyclovir and peniciclovir |
|
|
Term
| potent inhibition of CMV replication |
|
Definition
|
|
Term
| Structurally a nucleoside analog with more complex but poorly defined MOA; interference in transcription, depletion of intracellular pool of GTP |
|
Definition
|
|
Term
| Inorganic phosphate analog that inhibits several viral enzymes (DNA polymerase, reverse transcriptase) |
|
Definition
|
|
Term
| Interferes with uncoating and nucleic acid release of some RNA viruses, inhibition of M2 surface protein |
|
Definition
|
|
Term
| inhibits the hydrolysis of sialic acid by neuraminidase that is required for release of viral progeny |
|
Definition
| Neuraminidase (sialidase) inhibitors |
|
|
Term
| Competitive neuraminidase inhibitors |
|
Definition
| Oseltamivir (po) and zanamivir (inhaled) |
|
|
Term
|
Definition
| Valacyclovir, Valganiclovir |
|
|
Term
|
Definition
|
|
