Shared Flashcard Set

Details

Antiviral Drugs 2: HIV
Pharmacology Exam 2
39
Pharmacology
Professional
04/18/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
What is the mechanism of action for Zidovidine?
Definition
Viral Reverse Transcriptase Inhibition.
Term
What is the Indication for use of Zidovidine?
Definition
HIV
Term
What are the Main Toxicities of Zidovidine?
Definition
Bone Marrow Toxicity.

GI Intolerance.
Term
What is the mechanism of action of Didanosine?
Definition
Viral Reverse Transcriptase Inhibition.
Term
What is the indication for use of Didanosine?
Definition
HIV
Term
What are the main toxicities of Didanosine?
Definition
Peripheral neuropathy.

Pancriatitis.

GI Intolerance.
Term
What is the mechanism of action of Stavudine?
Definition
Viral Reverse Transcriptase Inhibiton.
Term
What are the indications for use of Stavudine?
Definition
HIV
Term
What are the main toxicities of Stavudine?
Definition
Peripheral Neuropathy.
Lactic Acidosis.
Term
What is the mechanism of action of Lamivudine?
Definition
Viral Reverse Transcriptase Inhibition.
Term
What are the indications of use for Lamivudine?
Definition
HIV.

Hepatitis B.
Term
What are the main toxicities of Lamivudine?
Definition
Nasal Congestion.

Nausea, malaise, fatigue.

flare of Hepatitis B.
Term
What is the mechanism of action of Abacavir?
Definition
Viral Reverse Transcriptase Inhibition.
Term
What is the indication for Abacavir?
Definition
HIV
Term
What are the main toxicities of Abacavir?
Definition
severe hypersensitivity.
Term
What is the mechanism of action of Emtricitabine?
Definition
Viral Reverse Transcriptase Inhibition.
Term
What are the indications for use of Emtricitabine?
Definition
HIV.

Hepatitis B.
Term
What are the main toxicities of Emtricitabine?
Definition
Hyperpigmentation of the palms and soles.
Term
What is the mechanism of action of Tenofovir?
Definition
Viral Reverse Transcriptase Inhibition.
Term
What are the indications for Tenofovir?
Definition
HIV.

Hepatitis B.
Term
What are the main toxicities of Tenofovir?
Definition
GI Disturbances.

Renal Toxicity.
Term
What is the mechanism of action of Nevirapine?
Definition
Reverse transcriptase inhibiton.

P450 Metabolism.
Term
What is the indication for Nevirapine?
Definition
HIV.
Term
What are the main toxicites of Nevirapine?
Definition
Hepatotoxicity.

Fever, nausea, and headache.

Rash.
Term
What is the mehcanism of action of Efavirenze?
Definition
Viral reverse transcriptase inhibition.

P450 Metabolism.
Term
What is the indication of Efavirenz?
Definition
HIV
Term
What are the main toxicities of Efavirenz?
Definition
Rash.

Dizziness, headache, insomnia.

Neural tube defects- not for pregnancy.
Term
What is the mechanism of action of Saquinavir?
Definition
Viral Protease Inhibition.

P450 Metabolism.
Term
What is the indication for use of Saquinavir?
Definition
HIV.
Term
What are the main toxicites of Saquinavir?
Definition
GI Disturbance.

ABNORMAL FAT DISTRIBUTION.

Aminotransferase increases.
Term
What is the mechanism of action of Ritonavir?
Definition
Viral Protease Inhibition.

P450 Metabolism
Term
What is the indication for use of Ritonavir?
Definition
HIV.
Term
What are the main toxicities of Ritonavir?
Definition
GI Disturbance.

Circumoral and Peripheral paresthesia.

Aminotransferase Increase.
Term
What is the mechanism of action of Indinavir?
Definition
Viral Protease Inhibition

P450 Metabolism
Term
What is the indication for Indinavir?
Definition
HIV.
Term
What are the main toxicities of Indinavir?
Definition
GI Disturbance.

Nephrolithiasis.

Hyperbilirubinemia.

Dermatological Changes.
Term
What is the mechanism of action for Nelfinavir?
Definition
Viral Protease inhibiton.

P450 Metabolism.
Term
What is the indication of use for Nelfinavir?
Definition
HIV.
Term
What is the main toxicity for Nelfinavir?
Definition
GI Disturbance.
Supporting users have an ad free experience!