Term
| What is the mechanism of action for Zidovidine? |
|
Definition
| Viral Reverse Transcriptase Inhibition. |
|
|
Term
| What is the Indication for use of Zidovidine? |
|
Definition
|
|
Term
| What are the Main Toxicities of Zidovidine? |
|
Definition
Bone Marrow Toxicity.
GI Intolerance. |
|
|
Term
| What is the mechanism of action of Didanosine? |
|
Definition
| Viral Reverse Transcriptase Inhibition. |
|
|
Term
| What is the indication for use of Didanosine? |
|
Definition
|
|
Term
| What are the main toxicities of Didanosine? |
|
Definition
Peripheral neuropathy.
Pancriatitis.
GI Intolerance. |
|
|
Term
| What is the mechanism of action of Stavudine? |
|
Definition
| Viral Reverse Transcriptase Inhibiton. |
|
|
Term
| What are the indications for use of Stavudine? |
|
Definition
|
|
Term
| What are the main toxicities of Stavudine? |
|
Definition
Peripheral Neuropathy.
Lactic Acidosis. |
|
|
Term
| What is the mechanism of action of Lamivudine? |
|
Definition
| Viral Reverse Transcriptase Inhibition. |
|
|
Term
| What are the indications of use for Lamivudine? |
|
Definition
|
|
Term
| What are the main toxicities of Lamivudine? |
|
Definition
Nasal Congestion.
Nausea, malaise, fatigue.
flare of Hepatitis B. |
|
|
Term
| What is the mechanism of action of Abacavir? |
|
Definition
| Viral Reverse Transcriptase Inhibition. |
|
|
Term
| What is the indication for Abacavir? |
|
Definition
|
|
Term
| What are the main toxicities of Abacavir? |
|
Definition
|
|
Term
| What is the mechanism of action of Emtricitabine? |
|
Definition
| Viral Reverse Transcriptase Inhibition. |
|
|
Term
| What are the indications for use of Emtricitabine? |
|
Definition
|
|
Term
| What are the main toxicities of Emtricitabine? |
|
Definition
| Hyperpigmentation of the palms and soles. |
|
|
Term
| What is the mechanism of action of Tenofovir? |
|
Definition
| Viral Reverse Transcriptase Inhibition. |
|
|
Term
| What are the indications for Tenofovir? |
|
Definition
|
|
Term
| What are the main toxicities of Tenofovir? |
|
Definition
GI Disturbances.
Renal Toxicity. |
|
|
Term
| What is the mechanism of action of Nevirapine? |
|
Definition
Reverse transcriptase inhibiton.
P450 Metabolism. |
|
|
Term
| What is the indication for Nevirapine? |
|
Definition
|
|
Term
| What are the main toxicites of Nevirapine? |
|
Definition
Hepatotoxicity.
Fever, nausea, and headache.
Rash. |
|
|
Term
| What is the mehcanism of action of Efavirenze? |
|
Definition
Viral reverse transcriptase inhibition.
P450 Metabolism. |
|
|
Term
| What is the indication of Efavirenz? |
|
Definition
|
|
Term
| What are the main toxicities of Efavirenz? |
|
Definition
Rash.
Dizziness, headache, insomnia.
Neural tube defects- not for pregnancy. |
|
|
Term
| What is the mechanism of action of Saquinavir? |
|
Definition
Viral Protease Inhibition.
P450 Metabolism. |
|
|
Term
| What is the indication for use of Saquinavir? |
|
Definition
|
|
Term
| What are the main toxicites of Saquinavir? |
|
Definition
GI Disturbance.
ABNORMAL FAT DISTRIBUTION.
Aminotransferase increases. |
|
|
Term
| What is the mechanism of action of Ritonavir? |
|
Definition
Viral Protease Inhibition.
P450 Metabolism |
|
|
Term
| What is the indication for use of Ritonavir? |
|
Definition
|
|
Term
| What are the main toxicities of Ritonavir? |
|
Definition
GI Disturbance.
Circumoral and Peripheral paresthesia.
Aminotransferase Increase. |
|
|
Term
| What is the mechanism of action of Indinavir? |
|
Definition
Viral Protease Inhibition
P450 Metabolism |
|
|
Term
| What is the indication for Indinavir? |
|
Definition
|
|
Term
| What are the main toxicities of Indinavir? |
|
Definition
GI Disturbance.
Nephrolithiasis.
Hyperbilirubinemia.
Dermatological Changes. |
|
|
Term
| What is the mechanism of action for Nelfinavir? |
|
Definition
Viral Protease inhibiton.
P450 Metabolism. |
|
|
Term
| What is the indication of use for Nelfinavir? |
|
Definition
|
|
Term
| What is the main toxicity for Nelfinavir? |
|
Definition
|
|
