Term
|
Definition
|
|
Term
|
Definition
active against lipid enveloped viruses
topical cream for herpes in immunocompetent pts |
|
|
Term
|
Definition
| interferes with virl fusion to host cell membrane |
|
|
Term
|
Definition
|
|
Term
|
Definition
treatment of influenza A virus infections
must be taken quickly after onset of symptoms |
|
|
Term
|
Definition
| blocks M2 H+ channel and prevents virus membrane uncoating |
|
|
Term
| inhibitors of reverse transcriptase |
|
Definition
AZT
3TC
entecavir
nevirapine and efavirenz |
|
|
Term
|
Definition
| used in combo to treat HIV infection |
|
|
Term
|
Definition
gets incorporated into viral DNA
cannot be added on to
terminates viral DNA |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| in combo with other anti-HIV drugs |
|
|
Term
|
Definition
| incorporated into viral DNA then terminates chain |
|
|
Term
| non-nucleoside Reverse transcriptase inhibitors |
|
Definition
|
|
Term
| nevirapine and efavirenz use |
|
Definition
combo with other anti-HIV drugs
only against HIV-1, not effective against HIV-2 |
|
|
Term
| nevirapine and efavirenz moa |
|
Definition
| inhibition of reverse transcriptase by binding to non-active site and causing structural change |
|
|
Term
| nevirapine and efavirenz resistance |
|
Definition
common
must be used with other drugs |
|
|
Term
|
Definition
|
|
Term
|
Definition
| for protease inhibitor HIV resistant strains |
|
|
Term
|
Definition
inhibits catalytic activity of HIV-1 integrase
stops provirus formation |
|
|
Term
| inhibitor of viral dna-dependent dna polymerase |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| incorporated into viral dna and terminates chain |
|
|
Term
| inhibitor of viral rna-dependent rna polymerase |
|
Definition
|
|
Term
|
Definition
| used with interferon to treat hep c |
|
|
Term
|
Definition
| causes abundant lethal mutations to viral dna |
|
|
Term
| inhibitor of viral protein synthesis |
|
Definition
|
|
Term
|
Definition
| treating chronic hep b and c |
|
|
Term
|
Definition
| stimulating degradation of ssrna and inactivation of protein synthesis machinery |
|
|
Term
| inhibitors of viral assembly - hiv protease inhibitors |
|
Definition
indinavir
nelfinavir
atazanzvir
saquinavir
ritonavir |
|
|
Term
| HIV protease inhibitors use |
|
Definition
|
|
Term
| hiv protease inhibitor moa |
|
Definition
bind to active site of protease resulting in inhibition of viral assembly
formed viruses are noninfective |
|
|
Term
|
Definition
|
|
Term
| oseltamivir and zanamivir use |
|
Definition
| influenze a and b treatment and prophylaxis |
|
|
Term
| oseltamivir and zanamivir moa |
|
Definition
| blocks releasing mechanism of virion during budding |
|
|
