Term
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Definition
atypical anti-psychotic
-increase QT interval -> arrythmias |
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Term
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Definition
atypical anti-psychotic
-potent D2 blocker
TX: schizo, schizoaffective DO, bipolar DO, mania, tourette's
TOX: low doses-dec. EPS, higher doses-inc. EPS w/ elevated prolactin
SEs: EPS, inc. prolactin, weight gain |
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Term
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Definition
atypical anti-psychotic
-blocks 5HT, D2, alpha-2 receptors
TX: schizo, schizoaffective DO, bipolar DO, mania, tourette's
TOX: weight gain, metabolic syndrome
-may help with negative signs |
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Term
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Definition
atypical anti-psychotic
-stronger D4 and 5HT, weaker D2 (many features like CPZ)
-may help with neg symptoms
TX: schizo, schizoaffective DO, bipolar DO, mania, tourette's
TOX: orthostatic hypotension, EPS, AGRANULOCYTOSIS, dec. seizure threshold, sialorrhea (M4) |
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Term
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Definition
atypical anti-psychotic
-partial D2 and 5HT1A agonist
TX: schizo, schizoaffective DO, bipolar DO, mania, tourette's
-less SEs
-minimal or no weight gain (as opposed to olanzopine) |
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Term
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Definition
typical anti-psychotic (low dose, high potency)
MOA: potent DA block
TX: schizo, schizoaffective DO, bipolar DO, mania, tourette's
TOX: severe EPS and TD, little CV or sedation, no anti-musc effects, NEUROLEPTIC MALIGNANT SYNDROME
-injectable prep available (IM) |
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Term
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Definition
typical anti-psychotic (high dose, low potency)
-blocks DA, alpha-1, muscarinic, histamine receptors
TX: schizo, schizoaffect DO, bipolar DO, mania, tourette's
TOX: DA-inc. EPS, prolactin, wt gain; mACH-anti-cholinergic effects; a1-orthostatic hypotension
-sedation, jaundice, photosensitivity, parkinsonism, TD, sexual dysfunction, arrythmias, anti-emetic effect (block CTZ)
-not drugs of abuse |
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