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Antiprotozoals
board prep
14
Medical
Graduate
04/13/2008

Additional Medical Flashcards

 


 

Cards

Term

 

 

 

Amebiasis (what is the DOC!)

Definition
Metronidazole
Term

 

 

 

Giardiasis (what is the DOC!)

Definition
Metronidazole (aka "backpacker's diarrhea)
Term

 

 

 

Trichomoniasis (what is the DOC!)

Definition
Metronidazole
Term

 

 

 

Pneumocystosis (what is the DOC!)

Definition
TMP-SMX
Term

 

 

 

Toxoplasmosis (what is the DOC!) 

Definition
Pyrimethamine + sulfadiazine
Term

 

 

 

Leishmaniasis (what is the DOC!)

Definition
Stibogluconate
Term

 

 

 

Trypanosomiasis (what is the DOC!)

Definition

Nifurtimox (chagas dz)

 

Arsenicals (african)

Term

 

 

 

Antimalarial DOC

Definition

If in chloroquine-sensitive region

 

P.falciparum, P.malariae : get chloroquine

P. vivax, P. ovale : get chloroquine + primaquine

 

If in chlorquine-resistant region

 mefloquine (prophylaxis), quinine + doxy/clindamycin or pyrimethamine (treatment)

 

 

Term

 

 

 

Chloroquine/ Hydroxychloroquine (SE's)

Definition

GI distress, pruritus, HA, dizziness, hemolysis, ocular dysfunction

 

Avoid in psoriasis

Term

 

 

 

Mefloquine (SE's)

Definition

NVD, dizziness, syncope, extrasystoles, CNS effects

 

Avoid in seizures, psychiatric disorders, cardiac conduction defects

Term

 

 

 

Primaquine (SE's)

Definition

GI distress, HA, dizziness, neutropenia, hemolysis

 

Avoid in pregnancy, G6PD def., and autoimmune

Term

 

 

 

Quinine (SE's)

Definition

GI distress, cinchonism, CNS effects, hemolysis, hematotoxicity

 

Avoid in pregnancy

Term

 

 

 

Intestinal nematodes (worms)

Definition

Mebendazole (dec. glucose uptake and microtubular structure)

 

Pyrantel pamoate: (NM agonist causes spastic paralysis)

Term

 

 

 

Cestodes (tapeworms) and trematodes (flukes)

Definition
Praziquantel (causes Ca2+ influx, and vacuolization)
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