Term
|
Definition
tx T. cruzi
produces intracellular free radicals to kill it |
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|
Term
|
Definition
| trivalent arsenical that binds/inhibits parasitic enzymes |
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|
Term
|
Definition
| inhibits ornithine decarboxylase |
|
|
Term
|
Definition
| tx T. gambiense and unwanted facial hair in women |
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|
Term
|
Definition
|
|
Term
| Metronidazole and Tinidazole |
|
Definition
|
|
Term
|
Definition
| disrupts electron transport chain in flagellate protozoa |
|
|
Term
|
Definition
resistance and lower disulfiram rxn disrupts DNA tertiary structure and inhibits DNA synthesis
anaerobic organisms |
|
|
Term
| Metronidazole and Tinidazole |
|
Definition
|
|
Term
| Metronidazole and Tinidazole |
|
Definition
| tx amebiasis (amebic dysentery) |
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|
Term
|
Definition
| use for amebiasis if not treated within two weeks (it is more powerful) |
|
|
Term
| Emetine and Dehydroemetine |
|
Definition
tx systemic amebiasis
cardiotoxic so rarely used |
|
|
Term
| Sulfadiazine (sulfonamide + pyrimethamine) |
|
Definition
| best tx for toxoplasmosis |
|
|
Term
|
Definition
new drug tx toxoplasmosis
inhibits mitochodrial ETC |
|
|
Term
| Primaquine and Clindamycin |
|
Definition
| new drugs indicated for Pneumocystosis |
|
|
Term
TMP-SMZ
Pentamidine
Atovaquone
Dapsone |
|
Definition
|
|
Term
|
Definition
| tx latent and hepatic forms of relapsing malaria |
|
|
Term
|
Definition
| cholorquine resistant malaria |
|
|
Term
| Malarone (Atovaquone and proguanil) |
|
Definition
|
|
Term
| Chloroquine and primaquine |
|
Definition
| key malaria drugs, but cause many resistant strains |
|
|
Term
|
Definition
tx malaria inhibits DNA synthesis
side effects "Cinchonism" = disorientation and other CNS problems |
|
|
Term
|
Definition
inhibits microtuble synthesis
(round, hook, pin, and whip worms) |
|
|
Term
|
Definition
| best antihelmintic! broad spectrum |
|
|
Term
|
Definition
| binds to chloride channels, causing hyperpolarization, paralysis, and death of nematodes |
|
|
Term
|
Definition
depolarizing neuromuscular blocking agent
paralyzes round and pin worms |
|
|
Term
|
Definition
| effective against microfilariae (W. bancrofti filariasis and elephantitis) |
|
|
Term
|
Definition
tx taenia (cestode)
alcohol = contraindication |
|
|
Term
|
Definition
| tx all cestodes and trematodes |
|
|
Term
|
Definition
| increases calcium permeability of membranes |
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|
