Term
|
Definition
first line tb
inhibits mycolic acid synthesis
(catalase-peroxidase rxn) |
|
|
Term
|
Definition
lupus like syndrome (anti DNA abs)
hepatotoxic
neurotoxic |
|
|
Term
|
Definition
first line tb
inhibits RNA synthesis by binding to DNA dependent RNA polymerase |
|
|
Term
|
Definition
| turns urine, sputum, feces, saliva red-orange |
|
|
Term
|
Definition
| contraindicated in patients taking PROTEASE INHIBITORS |
|
|
Term
|
Definition
| GI upset, hepatitis, proteinuria, skin rashes |
|
|
Term
|
Definition
first line tb
nicotinic acid derivative
very toxic |
|
|
Term
|
Definition
| polyarthralgia, myalgia, hepatic dysfunction |
|
|
Term
|
Definition
first line tb
unclear MOA
blocks some component of cell wall |
|
|
Term
|
Definition
green blindness
retinal damage
confusion, peripheral neuritis |
|
|
Term
|
Definition
2nd line Tb
protein synthesis inhibitor |
|
|
Term
|
Definition
2nd line tb
DNA synthesis inhibitor |
|
|
Term
|
Definition
2nd line tb
cell wall synthesis inhibitor |
|
|
Term
|
Definition
adverse effects:
restlessness, headache, CNS disorders |
|
|
Term
|
Definition
| most effective drug tx M. leprae |
|
|
Term
|
Definition
adverse effects:
GI, fever, methemoglobinemia, |
|
|
Term
|
Definition
| tx P. jirovecii in AID patients |
|
|
Term
|
Definition
repository form of dapsone
also inhibits folic acid synthesis |
|
|
Term
|
Definition
M. leprae tx
inhibits folic acid synthesis |
|
|
Term
|
Definition
| tx atypical mycobacterium |
|
|
