Term
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Definition
| Inhibit bacterial cell wall synthesis (block assembly of peptidoglycan). |
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Term
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Definition
| Inhibit bacterial cell wall synthesis (block assembly of peptidoglycan). |
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Term
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Definition
| Inhibits cell wall synthesis (block assembly of peptidoglycan). |
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Term
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Definition
| Inhibits cell wall synthesis (block assemply of peptidoglycan). |
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Term
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Definition
| Bind LPS and inhibit cell membrane function. |
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Term
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Definition
| Destroys cell membrane integrity by forming channels in the membrane. |
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Term
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Definition
| Blocks first step of folic acid synthesis (inhibits DNA formation). |
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Term
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Definition
| Blocks second step of folic acid synthesis (inhibits DNA formation). |
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Term
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Definition
| Causes fragmentation of bacterial and protozoal DNA. Undergoes reduction once inside cell and metabolite damages DNA. |
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Term
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Definition
| Induces DNA damage by being degraded inside cell and binds to DNA and causes strand breakage. |
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Term
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Definition
| Inhibit bacterial gyrase and/or topoisomerase IV. Inhibit DNA replication. |
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Term
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Definition
| Inhibit bacterial RNA polymerase, thus inhibits RNA synthesis. |
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Term
| Aminoglycosides and Spectinomycin |
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Definition
| Inhibits bacterial protein synthesis by binding to 30s rRNA. |
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Term
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Definition
| Inhibit bacterial protein synthesis by binding the 30s rRNA subunit. |
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Term
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Definition
| Inhibit bacterial protein synthesis by binding the 50s rRNA subunit. |
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Term
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Definition
| Inhibit bacterial protein synthesis by binding to 50s rRNA subunit. |
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Term
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Definition
| Inhibit bacterial protein synthesis by binding to 50s rRNA subunit. |
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Term
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Definition
| Inhibit fungal cell wall synthesis by preventing conversion of squalene to lanoesterol. |
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Term
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Definition
| Inhibit fungal wall synthesis by inhibiting the conversion of lanosterol to ergosterol. |
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Term
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Definition
| Bind fungal cell membrane ergosterol and inhibit membrane function. |
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Term
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Definition
| Inhibits fungal RNA and DNA synthesis in specific fungi. It is a structural analogue of cytosine. |
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Term
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Definition
| Inhibits fungal DNA replication, binds microtubules to prevent division of cells. |
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Term
| Organophosphates/Carbamates/Pyrethrins |
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Definition
| Neurotoxic to ectoparasites. |
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Term
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Definition
| Endectoside, neurotoxic to both internal and external parasites. |
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Term
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Definition
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Term
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Definition
| Neurotoxic to fleas (adults and larvae) and grubs. |
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Term
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Definition
| Neurotoxic to adult fleas and ticks. Blocks GABA gated channels (paralysis). |
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Term
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Definition
| Neurotoxic to adult fleas, blocks Na channels causing paralysis. |
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Term
| Lufenuron, Pyriproxyfen, Methoprene |
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Definition
| Insect growth inhibitor, inhibits chitin formation by killing epidermal cells responsible for making chitin. |
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Term
| Piperzine, levamisole, pyrantel/morantel |
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Definition
| Neurotoxic to nematodes (paralyzed by cholinergic antagonist). |
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Term
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Definition
| Neurotoxic to nematodes, causes influx of Ca and DAG into neuron and causes flaccid paralysis and death. |
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Term
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Definition
| Flukicide that causes starvation of flukes by inhibiting glycolytic enzymes. |
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Term
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Definition
| Kill tapeworms and flukes by damaging tegument. |
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Term
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Definition
| Kills all helminthes via starvation by interrupting energy metabolism. Kills eggs by binding to microtubules. |
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