Term
| Targets of antimicrobial agents overall effect |
|
Definition
*cell membrane
*cell wall
*protein syntheis
*metabolic reactions |
|
|
Term
|
Definition
| *penicillin *cephalosporin *vancomycin *bacitracin *monobactams *fosfomycin *cycloserine |
|
|
Term
| inhibit replication & translocation |
|
Definition
| *quinolone (Cipro) (inhibit unwinding) |
|
|
Term
|
Definition
|
|
Term
| inhibit folic acid metabolism |
|
Definition
| *sulfa drugs & trimethoprime |
|
|
Term
cell membrane
(EUK - sterols, fungi) |
|
Definition
| *polymyxins & Amphotericin B & nystatin |
|
|
Term
|
Definition
|
|
Term
| targeted Ribosomes/block protein synthesis: the 30S subunit |
|
Definition
| *aminoglycosides *tetracycline *streptomycin *Amikacin |
|
|
Term
| targeted Ribosomes/block protein synthesis: 50S subunit |
|
Definition
| *Chloramphenicol *erythromycin *clindamycin *Oxalolidinones |
|
|
Term
| Target bacterial cell wall/Pepticoglycan |
|
Definition
*penicillin (the cross linking)
*cephalosporin
(cause cell walls to lyse) |
|
|
