Term
| These are a group of broad spectrum antibiotics that would be more effective against more resistant pathogens. |
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Definition
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Term
Fluoroquinolones
Actions (1): |
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Definition
| -interfere w/ an enzyme needed by bacteria for the syntheses of DNA which prevents cell production |
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Term
Fluoroquinolones
Uses (4): |
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Definition
-Lower resp infections
-UTI
-STD
-Infections of eye |
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Term
Fluoroquinolones
Adverse Rx (5): |
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Definition
-Superinfections
-N/D
-Pseudomembranous Colitis-Diarrhea
-Dizzines
-Photosensitivity Reaction |
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Term
Fluoroquinolones
Contraindications (4): |
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Definition
-Hypersensitivity
-Children younger than 18
-PG women (catergory C)
-Lifestyles that would not adhere to the precautions of photosensitivity reactions |
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Term
Fluoroquinolones
Precautions (2): |
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Definition
-Renal Impairment
-Geriatric pts |
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Term
Fluoroquinolones
Interactions (3): |
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Definition
-Increase theophyline levels
-oral anticoags (increases serum levels of these)
-NSAIDs (put pt @ risk for seizures) |
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Term
do not give ____to children under 12!!!!!!!!!!
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Definition
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Term
| if drug ends in -mycin assess: |
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Definition
| Hearing & kidney function |
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Term
Misc Drugs
Vancomycin
Action (1): |
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Definition
| Inhibits bacterial cell wall synthesis |
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Term
Misc Drugs
Vancomycin
Uses (2): |
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Definition
-Serious gram postive that doesn't respond to other meds
-Effective in treating clostridium difficile |
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Term
Misc Drugs
Vancomycin
Adverse Rx (5): |
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Definition
-Nephrotoxicity: Proteinuria. (check ranal function by measuring I&O)
-Ototoxicity
-Nausea
-Uriticaria
-Drop in BP w/ parenteral administration |
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Term
Misc Drugs
Vancomycin
Contrainidcation (1): |
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Definition
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Term
Misc Drugs
Vancomycin
Precautions (2): |
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Definition
-Renal/hepatic impairment
-PG/Lactation |
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Term
Misc Drugs
Vancomycin
Interactions (1): |
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Definition
| -Additive effects when given w/ ototoxic/nephrotoxic drugs. |
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Term
Antitubercular Drugs
Actions (1):
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Definition
| -Bacteriostatic against mycobacterium TB. |
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Term
Antitubercular Drugs
Uses (1): |
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Definition
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Term
Antitubercular Drugs
____ most common drug, given with rifampin (turns secretions of body orange) |
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Definition
Isoniazid (INH)
**Lasts 2-3 months |
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Term
Antitubercular Drugs
Adverse Rx (5): |
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Definition
- N/V
-epigastric distress
-skin rashes
-jaundice
-hypersensitive
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Term
Antitubercular Drugs
Toxicity (2): |
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Definition
-Most Common: Peripheral Neuropathy: Numbness/tingling of extremities
-Severe to fatal hepatitis: may occur after months of Tx. |
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