| Term 
 | Definition 
 
        | end in -pril decrease blood pressure
 decrease aldosterone (sodium/fluid loss)
 
 for CHF & HTN
 
 gastric irritation, MI, hypotention, proteinuria, rash, pruritis, cough, peripheral edema
 
 do NOT take with food
 frequent mouth care
 used with thiazide diuretics
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        |  | 
        
        | Term 
 | Definition 
 
        | ends in -lol decreases beats, blood pressure
 (decreases workload and O2 consumption)
 
 helps with migraines and stage fright
 
 gastric pain, impotence, bronchospasm, nightmares, heart failure dysrhythmias, blocks hypoglycemia signs
 
 TAKE WITH MEALS
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Amlodipine (A) Verapimil (Very)
 Nifidipine (Nice)
 Diltiazem (Drug)
 
 dialates and slows impulse conduction in heart (decreased contractibility)
 
 nervousness, impotence, peripheral edema, flushing, rash, AV block
 
 sustain release tabs (do NOT chew), avoid grapefruit juice, notify MD of low BP, contraindicated in heart block
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | ends in -sartan 
 HTN, HF, MI, stroke prevention AND diabetic neuropathy
 
 causes angioedema (monitor and call MD)
 renal failure, ortho hypotension
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | ends in -osin blocks receptors in PERIPHERAL blood vessels
 
 HTN, Raynauds, BPH
 
 reflex tachy, nasal congestion, impotence
 
 monitor BUN/Cr, wt, edema; TAKE AT BED
 |  | 
        |  | 
        
        | Term 
 
        | Centrally acting alpha-adrenergics |  | Definition 
 
        | Clonodine (Catapres) Methyldopa (Aldomet)
 
 causes reduction in sympathetic axn in heart by affecting receptors in medulla
 
 decrease CO, rate, and force of contraction
 
 drowsiness, sedation, ortho hypo, CHF
 
 monitor for fluid overload
 |  | 
        |  | 
        
        | Term 
 
        | Direct-acting vasodialators |  | Definition 
 
        | Hydralazine (Apresoline) Minoxidil
 
 relaxes smooth muscle blood vessels; lowers periph resistance
 
 drowsiness, ortho hypotension, sedation, CHF
 
 monitor fluid retention
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