Term
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Definition
Mechanism- works on alpha 2 site to prevent NE release- dec. sympathetic output
prodrug- active when metabolized
S.E.- depression, drowsiness, impaired ejaculation |
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Term
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Definition
Mechanism- works on alpha 2 site to prevent NE release- dec. sympathetic output
S.E.- depression, drowsiness, impaired ejaculation
sudden withdrawl can cause hypertensive emergency
unlisted uses- help with opiate withdrawal, fibromyalgia, insomnia |
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Definition
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Definition
Mechanism- inhibits tyrosine hydrooxylase- prevents synthesis of NE and EP
used to treat pheochromocytoma |
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Definition
Mechanism- totally block all ganglionic transmission- block nitotinic receptors
S.E.- orthostatic hypertension |
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Term
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Definition
Mechanism- totally block all ganglionic transmission- block nitotinic receptors
S.E.- orthostatic hypertension |
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Term
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Definition
Mechanism-prevents encorporation of NE into vesicles, depletion of NE- also works on CNS
S.E.- depression (suicides), drowsiness, diarrhea, impaired ejaculation |
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Term
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Definition
Mechanism-depletes NE from post ganglionic neurons, does not enter CNS
S.E- orthostatic hypertension |
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Term
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Definition
Mechanism- alpha 1 blocker
block effect of NE on end organ receptor |
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Term
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Definition
Mechanism- alpha 1 blocker
block effect of NE on end organ receptor |
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Term
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Definition
Mechanism- alpha 1 blocker
block effect of NE on end organ receptor |
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Term
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Definition
Mechanism- alpha 1 blocker used for treatment of benign prostatic hypertophy (BPH)
S.E.-first dose effect- fast orthostatic hypotension, can be avoided by taking at night before sleep |
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Term
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Definition
Mechanism- alpha 1 blocker used for treatment of benign prostatic hypertophy (BPH)
S.E.-first dose effect- fast orthostatic hypotension, can be avoided by taking at night before sleep |
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Term
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Definition
Mechanism- blocks all Beta receptors
blocks B1 on heart and slows heart down
gets into CNS
S.E.- depression, fatigue, can cause asthma because it prevents dialation of bronchiole |
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Term
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Definition
Mechanism- Beta 1 blocker
doesn't enter CNS
S.E.- fatigue and bradycardia |
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Term
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Definition
Mechanism- Beta 1 blocker
doesn't enter CNS
S.E.- fatigue and bradycardia |
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Term
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Definition
Mechanism- Beta 1 blocker
doesn't enter CNS
S.E.- fatigue and bradycardia |
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Term
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Definition
| Mechanism- Beta 1 blocker that also increases NO and causes vasodilation |
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Term
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Definition
| Mechanism- combined alpha and beta blocker |
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Term
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Definition
| Mechansim- combined alpha and beta blocker |
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Term
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Definition
Mechanism- blocks angiotension receptor
S.E.- fetal abnormalities |
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Term
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Definition
Mechanism- blocks angiotension receptor
S.E.- fetal abnormalities |
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Term
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Definition
Mechanism- blocks angiotension receptor
S.E.- fetal abnormalities |
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Term
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Definition
Mechanism- blocks angiotension receptor
S.E.- fetal abnormalities |
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Term
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Definition
Mechanism- blocks angiotension receptor
S.E.- fetal abnormalities |
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Definition
Mechanism- blocks angiotension receptor
S.E.- fetal abnormalities |
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Term
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Definition
Mechanism- acts directly on smooth muscle and opens K+ channels
S.E.- causes hair growth- hypertrichosis
used to treat edema, pericardial effusion |
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Term
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Definition
Mechanism- acts directly on smooth muscle
opens K+ channels
S.E.- dec. insulin secretion |
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Term
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Definition
Mechanism- acts directly on smooth muscle
inc. cGMP
S.E. can cause loupous like symptoms in slow accelators |
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Term
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Definition
Mechanism- acts directly on smooth muscle
inc. cGMP- acts on all vasculature and is given IV and acts in seconds
S.E.- degrades into cyanide so must be made on the spot
is the drug of choice for hypertensive emergencies |
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Term
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Definition
| Mechanism- Calcium channel blocker- causes vasodilation by dec. Ca2+ uptake into smooth muscle vasculature |
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Term
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Definition
| Mechanism- Calcium channel blocker- causes vasodilation by dec. Ca2+ uptake into smooth muscle vasculature |
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Term
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Definition
| Mechanism- Calcium channel blocker- causes vasodilation by dec. Ca2+ uptake into smooth muscle vasculature |
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Definition
Mechanism-inhibits formation of angiotensin by inhibiting angiogensin converting enzyme (ACE) which converts angiotensin I into angiotenin II- also prevents breakdown of bradykinin because ACE breaks down bradykinin
S.E.- dry cough that doesn't respond to meds, fetal abnormalities |
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Term
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Definition
Mechanism-inhibits formation of angiotensin by inhibiting angiogensin converting enzyme (ACE) which converts angiotensin I into angiotenin II- also prevents breakdown of bradykinin because ACE breaks down bradykinin
S.E.- dry cough that doesn't respond to meds, fetal abnormalities |
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Term
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Definition
Mechanism-inhibits formation of angiotensin by inhibiting angiogensin converting enzyme (ACE) which converts angiotensin I into angiotenin II- also prevents breakdown of bradykinin because ACE breaks down bradykinin
S.E.- dry cough that doesn't respond to meds, fetal abnormalities |
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Term
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Definition
Mechanism-inhibits formation of angiotensin by inhibiting angiogensin converting enzyme (ACE) which converts angiotensin I into angiotenin II- also prevents breakdown of bradykinin because ACE breaks down bradykinin
S.E.- dry cough that doesn't respond to meds, fetal abnormalities |
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Term
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Definition
Mechanism-inhibits formation of angiotensin by inhibiting angiogensin converting enzyme (ACE) which converts angiotensin I into angiotenin II- also prevents breakdown of bradykinin because ACE breaks down bradykinin
S.E.- dry cough that doesn't respond to meds, fetal abnormalities |
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Term
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Definition
Mechanism- direct inhibitor of renin
S.E.- dry cough, fetal abnormalities |
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Term
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Definition
Mechanism-acts directly on dopamine receptors in muscle
given IV for hypertensive emergencies |
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