Term
HMG-CoA Reductase Inhibitors
(Statins) |
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Definition
Lovastatin (Mevacor®)
Simvastatin (Zocor®)
Pravastatin (Pravachol®)
Fluvastatin (Lescol®)
Rosuvastatin (Crestor®)
Atorvastatin (Lipitor®)
Pitavastatin (Livalo®)
MOA: Block the synthesis of cholesterol through inhibition of HMG-CoA Reductase
Lowers LDL, Raises HDL |
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Term
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Definition
Mevacor®
Dose: 10 mg
HMG-CoA Reductase Inhibitors (Statins) |
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Term
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Definition
Zocor®
Dose: 10 mg
HMG-CoA Reductase Inhibitor (Statin) |
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Term
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Definition
Pravachol®
Dose: 20 mg
Only statin that is not metabolized through CYP450
HMG-CoA Reductase Inhibitor (Statin) |
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Term
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Definition
Lescol®
Dose: 10 mg
HMG-CoA Reductase Inhibitor (Statin) |
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Term
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Definition
Crestor®
Dose: 5 mg
HMG-CoA Reductase Inhibitor (Statin) |
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Term
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Definition
Lipitor®
Dose: 10 mg
HMG-CoA Reductase Inhibitor (Statin) |
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Term
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Definition
Livalo®
Dose: 4 mg
HMG-CoA Reductase Inhibitor (Statin) |
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Term
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Definition
Gemfibrozil (Lopid®)
Fenofibrate (Tricor®)
MOA: Act at the site of peroxisome proliferator activated receptor (PPAR)
Lower Triglycerides, LDL, and Raise HDL (To a lesser extent than the statins) |
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Term
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Definition
Lopid®
Fibrinic Acid Derivative |
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Term
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Definition
Tricor®
Fibrinic Acid Derivative |
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Term
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Definition
Niaspan®
Vitamin B3
MOA: Not Known
Niacin |
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Term
Bile Acid-Binding Resins
(Bile Acid Sequestrants) |
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Definition
Cholestyramine (Cuemid®, Questran®)
Colestipol (Colestid®)
Colesevelam (Welchol®)
MOA: Binds with bile acids in the GI tract to decrease fat absorption
Decreased Triglycerides |
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Term
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Definition
Questran®, Cuemid®
Bile Acid Sequestrant |
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Term
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Definition
Colestid®
Bile Acid Sequestrant |
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Term
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Definition
Welchol®
Bile Acid Sequestrant |
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Term
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Definition
Ezetimibe (Zetia®)
MOA: Inhibits cholesterol absorption at small intestine brush border
Lowers LDL and Triglycerides, Raises HDL (slightly) |
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Term
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Definition
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