Term
|
Definition
MOA: Blocks H1 receptors to inhibit the release of histamine
SE: Anticholinergic side effects, sedation, drowsiness |
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Term
Aminoalkyl ethers
(ethanolamines) |
|
Definition
Diphenhydramine HCl (Benadryl®)
Dimenhydrinate (Dramamine®)
Doxylamine Succinate (Decapryn®)
Carbinoxamine Maleate (Clistin®)
Clemastine fumarate (Tavist®)
Phenyltoloxamine (Dologesic, Lagesic®) |
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Term
|
Definition
Benadryl®
Dose: 25 mg IV or Oral
Available as IM, IV, PO
Aminoalkyl esters (ethanolamines) |
|
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Term
|
Definition
Dramamine®
Use: Motion sickness, Nausea during pregnancy
Combination of diphenhydramine and a-Chlorotheopylline
Aminoalkyl ethers (ethanolamines) |
|
|
Term
|
Definition
Decapryn®
Aminoalkyl ethers (ethanolamines) |
|
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Term
|
Definition
Clistin®
A racemic mixture
Aminoalkyl ethers (ethanolamines) |
|
|
Term
|
Definition
Tavist®
Also has antimuscarinic activity
Aminoalkyl ethers (ethanolamines) |
|
|
Term
|
Definition
Dologesic®, Lagesic®
Not available as a single agent, available in combo with Acetaminophen
Aminoalkyl ether (ethanolamines) |
|
|
Term
Propylamines
(Monoaminopropyl derivatives) |
|
Definition
Chlorpheniramine maleate (ChlorTrimeton®)
Triprolidine HCl (Aprodine®) |
|
|
Term
|
Definition
ChlorTrimeton®
Half life: 12-15 hours
Dose: 4 mg
Propylamines (Monoaminopropyl derivatives) |
|
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Term
|
Definition
Aprodine®
Not available as a single agent, in combination with Pseudoephedrine
Propylamine (Monoaminopropyl derivatives) |
|
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Term
|
Definition
Cyclizine HCl (Marezine®)
Meclizine (Bonine®, Antivert®) |
|
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Term
|
Definition
Marezine®
Use: Motion sickness
Piperazine (Cyclizines) |
|
|
Term
|
Definition
Bonine®, Antivert®
Use: Motion sickness
Antivert is the brand name for the prescription product and Bonine is the OTC brand
Piperazine (Cyclizines) |
|
|
Term
|
Definition
Phenergan®
Dose: 25 mg
Phenothiazine |
|
|
Term
|
Definition
Periactin®
Possesses both antihistamine and antiserotonin activity
Dibenzocycloheptenes/Heptanes |
|
|
Term
|
Definition
Bromfed®
1st Generation Antihistamine |
|
|
Term
2nd Generation Antihistamines |
|
Definition
Fexofenadine (Allegra®)
Loratadine (Claritin®)
Desloratadine (Clarinex®)
Cetirizine (Zyrtec®)
Levocetirizine (Xyzal®) |
|
|
Term
|
Definition
Allegra®
Oxadized metabolite of Terfenadine
2nd Generation Antihistamine |
|
|
Term
|
Definition
Claritin®
Structurally similar to dibenzocycloheptenes/heptanes, Half life: 8-15 hours
2nd Generation Antihistamine |
|
|
Term
|
Definition
Clarinex®
Metabolite of Loratadine, considered non-sedating
Only available as a prescription
2nd Generation Antihistamine
|
|
|
Term
|
Definition
Zyrtec®
2nd Generation Antihistamine |
|
|
Term
|
Definition
Xyzal®
Metabolite of Cetirizine, considered nonsedating
2nd Generation Antihistamine |
|
|
Term
|
Definition
Azelastine (Astelin®)
Emedastine (Emadine®)
Levocabastine (Livostin®)
Olopatadine (Patanol®) |
|
|
Term
|
Definition
Astelin®
Nasal spray for allergic rhinitis
Topical Antihistamine |
|
|
Term
|
Definition
Emadine®
Eye drop for allergic conjunctivitis
Topical Antihistamine |
|
|
Term
|
Definition
Livostin®
Eye drops for allergic conjunctivitis
Topical Antihistamine |
|
|
Term
|
Definition
Patanol®, Patanase®
Eye drops and Nasal spray
Topical Antihistamine |
|
|
Term
|
Definition
Cimetidine (Tagamet®)
Famotidine (Pepcid®)
Ranitidine (Zantac®)
Nizatidine (Axid®)
MOA: Blocks H2 receptors to inhibit the production of stomach acid |
|
|
Term
|
Definition
Tagamet®
Inhibitor of CYP450, Half life: about 2 hours
H2 Antagonist |
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Term
|
Definition
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Term
|
Definition
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Term
|
Definition
|
|
Term
|
Definition
Cromolyn Sodium (Intal®)
Nedecromil (Tilade®)
MOA: Works to stabilize mast cells and inhibit them from destabilizing which helps decrease histamine release |
|
|
Term
|
Definition
Intal®
Used in patients with asthma and COPD
Mast Cell Stabilizer |
|
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Term
|
Definition
Tilade®
Mast Cell Stabilizer |
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