Term
|
Definition
-adjunct in treatment of anaphylactic shock
-urticaria and pruritis
-rhinitis |
|
|
Term
|
Definition
peptic ulcer disease
GERD
(reduction of acid secretion in stomach) |
|
|
Term
| Which generation of H1 blockers do not cross the BBB to any extent? |
|
Definition
|
|
Term
| 1st generations are _____ drugs. |
|
Definition
|
|
Term
| 1st generations also block... |
|
Definition
-muscarinic receptors
-alpha receptors
-5-HT receptors
-Na channels |
|
|
Term
| 1st generation indications |
|
Definition
-acute and chronic allergic rhinitis
-vasomotor rhinitis
-eosinophilic nonallergic rhinitis
-viral URI
-urticaria
-allergic conjunctivitis
-anaphylactic reactions (add to epi)
-motion sickness/nausea (H1 and m)
-insomnia (H1 and m) |
|
|
Term
| rhinitis symptoms treated by 1st generations |
|
Definition
sneezing (H1)
itching (H1)
rhinorrhea (m)
sinus congestion is NOT treated |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| 1st generation side effects |
|
Definition
sedation
CNS effects
dry mouth
blurred vision
urinary retention |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| key points about 2nd generations |
|
Definition
-less complete distribution to CNS so less sedation compared to 1st generations
-longer half life therefore longer duration of action |
|
|
Term
| rhinitis symptoms treated by 2nd generations |
|
Definition
sneezing (H1)
itching (H1)
sinus congestion is NOT treated
rhinorrhea is NOT treated |
|
|
Term
|
Definition
alpha agonist
oral decongestant |
|
|
Term
|
Definition
alpha agonist
oral decongestant |
|
|
Term
| alpha agonists mechanism of action |
|
Definition
| cause vasoconstriction, reduce edema |
|
|
Term
| oral decongestant effects |
|
Definition
-reduce sinus congestion
-reduce fluid in Eustacian tubes
-DO NOT reduce sneezing, itching, rhinorrhea
-raise BP
-myadriatic |
|
|
Term
| Oral decongestants are commonly combined with... |
|
Definition
|
|
Term
| Oral decongestants may cause... |
|
Definition
|
|
Term
| Other therapy for rhinitis that inhibits degranulation of mast cells |
|
Definition
| intranasal cromolyn sodium (nedocromil) |
|
|
Term
|
Definition
|
|
Term
|
Definition
| claimed to facilitate removal of viscous mucus (expectorant) |
|
|
Term
|
Definition
| claimed to decrease viscosity of mucus (expectorant) |
|
|
Term
|
Definition
| non-opioid, local anesthetic (lung) used as an antitussive |
|
|
Term
|
Definition
OTC opioid used as antitussive
central suppression of cough reflex
lacks addictive properties |
|
|
