Term
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Definition
| antihelmintic- DOC Nematodes. oral, poorly absorbed. interfers w. microtubules/ mitosis of parasite. CI in preggo. AE abd pain, diarrhea |
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Term
| Pyrantel pamoate (antiminth) |
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Definition
| antihelmintic- Nematodes. neuromuscular blockade in worm, paralyzes it. DOC A. lumbricoids (round worms). milde GI AE |
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Term
|
Definition
| antihelmintic- Nematodes. in terferes w. microtubules/mitosis of parasite. rapidly absorbed orally. DOC S. stercoralis, cutaneous larval migrains, trichinosis. GI & rash AE |
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Term
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Definition
| antihelmintic- Nematodes, DOC onchocerca. targets glutamate- gated chloride channels, paralyzes worm. AE mazotti like reaction, fever, ha, somnolence hTN. CI preggo & meningitis |
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Term
| praziquantel (biltricide) |
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Definition
| antihelmintic- Trematodes, flat worms, flukes. increase Ca2+ permeability- contract/paralyze worms. AE drowsy, dizzy, malaise, anorexia, GI, drug interactions CI preggo, lactation, & ocular cysticercosis. |
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Term
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Definition
| antihelmintic- Cestodes, tape worms. blocks ATP synthesis |
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