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Antifungals
Drugs
7
Art/Design
3rd Grade
05/01/2014

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Cards

Term
Fluconazole
Definition
Fungal infections due to sensitive years, Cryptococcus neoformans (meningitis), Coccidioides immitis (AKA "valley fever"); Antifungal prophylaxis- high risk patients: ex bone marrow transplants
Term
Itraconazole
Definition
Treatment of blastomycosis and histoplasmosis; first azole with activity against Aspergillus sp- supplanted by voriconazole; dermatophytosis
Term
Voriconazole
Definition
localized and systemic fungal infections: first line for invasive aspergillosis, first line for scedosporium sp. infections; antifungal prophylaxis
Term
Posaconazole
Definition
localized and systemic fungal infections; salvage therapy of refractory invasive fungal infections; antifungal prophylaxis
Term
Echinocandins (Capsofungin, Micafungin, Anidulafungin)
Definition
FIrst line: non-albicans sp. infections (candidemia nad invasive candida infections); second line: invasive aspergillosis, esophageal candidiasis; febrile neutropenic patients with suspected fungal infection, antifungal prophylaxis in hematopoietic stem cell transplant patients
Term
Amphotericin B
Definition
severe systemic and CNS infections of susceptible fungi; local administration: fungal cystitis, had been used for cases of resistant thurs but currently rarely utilized
Term
Flucytosine
Definition
Cryptococcal infections; used in combo with either ampho B or fluconazole; distributes well into CSF
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