Term
|
Definition
INJ/TOP
BROAD
ergosterol – pores
resistance possible |
|
|
Term
|
Definition
ORAL/TOP
CANDIDAL
ergosterol – pores
resistance possible |
|
|
Term
|
Definition
ORAL/TOP
ergosterol – synth
H. sterol & cyt p450 INHIBIT
Resistance in long, cross |
|
|
Term
CLOTRIMAZOL/MICONAZOL
AZOLES |
|
Definition
TOP/VAGINA
Ergosterol – synth
Resistance in long, cross |
|
|
Term
|
Definition
CNS/ORAL;
Ergosterol –synth
RENAL EXCRETE 75%
Resistance in long, cross |
|
|
Term
TERBINAFINE (TOLNAFTATE)
ALLYLAMINE |
|
Definition
Ergosterol – synth
ORAL/TOP
KERATINE BOUND (skin, hair, nail)
NO RESISTANCE |
|
|
Term
ANIFULAFUNGIN
ECHINOCANDINS |
|
Definition
INHIBIT b-Glucan Synth
INVASIVE CANDIDA
LONG LAST
RESISTANCE SLOW
IV |
|
|
Term
|
Definition
INHIBIT b-Glucan Synth
MUCOCUTANIOUS CANDIDA
RESISTANCE SLOW
IV |
|
|
Term
CASPOFUNGIN
ECHINOCANDINS |
|
Definition
INHIBIT b-Glucan Synth
BOTH CANDIDA TYPES
RESISTANCE SLOW
IV |
|
|
Term
FLUCOCYTOCINE
ANTIMETABOLITES |
|
Definition
DNA SYNTH INIBIT
RESISTANCE DEVELOP
COMBINATION USED
RENAL EXCRETION |
|
|
Term
|
Definition
MT NOT FORM
LIVER ENZYME INCREASED
KERATINE BOUND, SKIN/HAIR/NAIL ONLY
NO RESISTANCE |
|
|
