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Antidotes
specific antidotes for various overdoses
22
Pharmacology
Graduate
04/10/2013
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Term
acetaminophen
 Definition
N-acetylcysteine. replenishes glutathione.
Term
salicylates
 Definition
bicarb to alkalinize urine, dialysis
Term
amphetamines (basic)
 Definition
NH4Cl to acidify urine
Term
acetylcholinesterase inhibitors/organophosphates
 Definition
atropine + pralidoxime
Term
antimuscarinic, anticholinergic agents
 Definition
physostigmine salicylate
Term
beta-blockers
 Definition
glucagon
Term
digitalis
 Definition
normalize K+, Lidocaine, Digibind, Mg2+
Term
Iron (also Aluminum)
 Definition
deferoxamine
Term
Lead
 Definition
CaEDTA, dimercaprol, succimer, penicillamine
Term
mercury, gold, arsenic
 Definition
dimercaprol, succimer
Term
copper, arsenic, gold
 Definition
penicillamine
Term
cyanide
 Definition
nitrite, hydroxycobalamin, thiosulfate
Term
methemoglobin
 Definition
methylene blue, vitamin C
Term
carbon monoxide
 Definition
100% O2, hyperbaric O2
Term
methanol, ethylene glycol
 Definition
fomepixole, ethanol, dialize
Term
opioids
 Definition
naloxone/naltrexone
Term
benzodiazepines
 Definition
flumazenil
Term
TCAs
 Definition
bicarb to alkalinize plasma
Term
heparin
 Definition
protamine
Term
warfarin
 Definition
Vitamin K, fresh frozen plasma
Term
tPA
 Definition
aminocaproic acid
Term
theophylline
 Definition
beta-blocker
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