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Antidiabetics
Part 3
19
Nursing
Graduate
11/17/2014

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Cards

Term
WHAT IS THE PEAK AND DURATION OF GLYBURIDE? WHAT TYPE OF EFFECT DOES GLYBURIDE HAVE ON VOLUME?
Definition
3 HR PEAK AND 24 HR DURATION. MILD DIURETIC EFFECT
Term
WHAT IS THE PEAK, DURATION, AND VOLUME EFFECT OF GLIPIZIDE?
Definition
FASTER ONSET <3HRS, SHORTER DURATION <24 HRS, MILD DIURETIC EFFECT.
Term
GLIMEPIRIDE IS SIMILAR TO ONSET, AND DURATION COMPARED TRO WHAT OTHER SULFONYLUREAS DRUG?
Definition
GLIPIZIDE
Term
WITH POTASSIUM EFFLUX AND WHEN POTASSIUM STAYS INSIDE THE CELL WHAT HAPENS TO INSULIN SECRETION?
Definition
FOR A PANCREATIC BETA CELL. POTASSIUM EFFLUX= DECREASE INSULIN SECRETION. WHEN POTASSIUM STAYS INSIDE OF THE CELL INCREASE INSULIN SECRETION
Term
WHAT ARE MEGLITINIDES MOA?
Definition
SAME AS SULFONYLUREAS. INCREASE AMOUNT OF INSULIN SECRETED. MORE PROMPT ONSET AND SHORTER DURATION
Term
WHAT IS THE PEAK AND DURATION OF MEGLITINIDES? WHAT IS A SIDE EFFECT.
Definition
PEAK IS 1 HR, DURATION IS 4 HRS. SIDE EFFECTS IS LESS HYPOGLYCEMIA.
Term
WHAT ARE 2 MEDICATIONS IN THE MEGLITINID CLASSIFICATION?
Definition
REPAGLIDIDE AND NATEGLINIDE. KNOW THAT THEY END IN GLINIDE
Term
WHAT IS A DRUG THAT IS IN THE CLASSIFICATION OG BIGUANIDES?
Definition
METFORMIN
Term
DOES METFORMIN IN THE CLASSIFICATION BIGUANIDES HAVE A LOW RISK OF HYPOGLYCEMIA?
Definition
VERY LOW RISK OF HYPOGLYCEMIA
Term
METFORMIN IS BENEFICIAL IN NOT ONLY DECREASING GLUCOSE BUT WHAT OTHER 2 THINGS?
Definition
REDUCING SERUM LIPID AND DECREASE WEIGHT
Term
BIGUANIDES (METFORMIN) HAS WHAT EFFECTS THAT DECREASE CANCERS, MIS, AND AMONG OTHERS?
Definition
AMPK
Term
WHAT IS THE MOA OF BIGUANIDES?
Definition
DECREASE GLUCOSE PRODUCTION IN THE LIVER BY TRIGGERING AMPK.
Term
WHAT IS THE PEAK AND DURATION OF METFORMIN?
Definition
2 HR PEAK AND 18 HR DURATION
Term
WHAT IS THE METABOLISM AND EXCRETION OF METFORMIN?
Definition
METFORMIN IS NOT METABOLIZED AND HAS RENAL EXCRETION THAT IS UNCHANGED
Term
WHAT ARE 2 SIDE EFFECTS OF METFORMIN?
Definition
GI DISTURBANCES AND LACTIC ACIDOSIS
Term
WHEN SHOULD METFORMIN BE DISCONTINUED PREOP?
Definition
48-72 HRS
Term
WHAT TYPES OF FLUIDS ARE CONTRAINDICATED WITH METFORMIN USE?
Definition
LR. USE NS INSTEAD
Term
METFORMIN BLOCKS THE HEPATIC METABOLISM OF WHAT?
Definition
LACTIC ACIDOSIS
Term
WHEN DO YOU HAVE INCREASED RISK OF DEVELOPING LACTIC ACIDOSIS WITH METFORMIN USE?
Definition
INCREASED RISK WITH HYPOVOLEMIA, HEPATIC DISEASE, RENAL DISEASE, IV CONTRAST ADMINISTRATION, ACUTE MI, CHF, SEPSIS OR ACIDOSIS, AND HYPOXEMIA.
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