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Antidepressants
na
5
Pharmacology
Professional
05/02/2010

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Cards

Term
clomipramine (Anafranil)
Definition
-tricyclic antidepressant
-can interact with sedatives to increase CNS depression
Term
phenelzine (Nardil)
Definition
antidepressant
Term
venlafaxine (Effexor)
Definition
-drug for depression
-SNRI class—serotonin PLUS norepi reuptake inhibitor
-Blocks removal of both NE and 5HT, to elevate their levels in the CNS and perhaps desensitize their receptors
Term
bupropion (Wellbutrin)
Definition
-DA and 5-HT reuptake inhibitor
-Used to treat depression with psychomotor retardation
-also used for nicotine addiction
-side effects include nervousness, insomnia, doesn’t react well with other sedatives
Term
lithium
Definition
-used to treat manic depression
-likely acts by modifying NE and 5HT neurotransmission, or IP3 inside neurons
-can cause dry mouth
-can’t take NSAIDs with this—may lead to elevated blood levels of the drug, resulting in OD and coma
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