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Anticoagulants/antifibrinolytics
Anticoagulants/antifibrinolytics
11
Pharmacology
Professional
03/03/2010

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Cards

Term
abciximab
Definition
monoclonal Ab, blocks IIb, IIIa, preventing platelet aggregation
Term
alteplase
Definition
recombinant TPA (fibrinolytic). plasmin breaks down fibrinogen and fibrin
Term
aminocaproic acid
Definition
prevents conversion of plasminogen to plasmin
Term
clopidogrel
Definition
blocks ADP binding sites, preventing platelet activation
Term
desmopressin
Definition
increases level of factor VIII, for hemophiliacs. acts like ADH
Term
enoxaparin
Definition
longer duration than heparin...for outpatient because give subQ. Low MW heparin. Primarily acts at X
Term
heparin
Definition
indirect thrombin inhibitor by activating ATIII, which inhibits II, IX, X
Term
phytonadione
Definition
vitamin K analogue
Term
protamine sulfate
Definition
antidote to heparin
Term
streptokinase
Definition
stimulates plaminogen to plasmin. must complex with something to work (unlike alteplase)
Term
warfarin
Definition
blocks regeneration of Vit K. Can't eat spinach. highly bound to albumin. P450 means lots of drug interactions. affected by what you eat.
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