| Term 
 | Definition 
 
        | • 50 u/kg • For acute myocardial infarction (AMI) 5000u loading and 1000 u/hr
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | • .25 mg/kg bolus • Then .125 mcg/kg/min for MI
 • For PCI post, 10 mcg/kg/min for 12 hours
 |  | 
        |  | 
        
        | Term 
 
        | Tirofiban HCl (Aggrastat) |  | Definition 
 
        | • Initial dose of 0.4 mcg/kg/min for 30 minutes • Followed by 0.1 mcg/kg/min for 48 to 108 hours or 12 – 24 hours after coronary intervention
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | • Initially, 1 mg/kg IV bolus just before PCI • Infusion at 2.5 mg/kg/hr for 4 hours
 • Administer another IV infusion at 0.2 mg/kg/hr for up to 30 hours as needed
 • Store prepared solution for up to 24 hours at 36 to 46 degrees Fahrenheit
 • Give with 325 mg of aspirin
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | • Begin infusion of 25 mcg/kg/min and administer bolus dose of 350 mcg/kg (over 3 to 5 minutes) • ACT should be checked 5 to 10 minutes after bolus
 • Proceed with procedure if ACT is > 300 seconds
 |  | 
        |  | 
        
        | Term 
 
        | Integrilin (Eptifibatide) |  | Definition 
 
        | • For MI 180 mcg/kg bolus then 2 mcg/kg/min for 72 hours • For PCI 135 mcg/kg bolus then .5 mcg/kg/min
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | • 1 mg/kg BID with ASA for 2 - 8 days |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | • 1 mg neutralizes 100 units of heparin • 50 mg max in a 10 minute period
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | • Loading 6 - 10 mg over 1 - 2 min • 60 mg over the first hour
 • Second and third hours 20 mg each
 • Weight < 65 kg give 1.25 mg/kg over three hours
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | • 10 units over 2 min • Repeat 10 unit in thirty minutes
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | 1ml, 2ml, 5ml, given 3 - 5 min apart |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | • 6.25 mg to 25 mg TID • Advance to 25 mg TID
 • Not to exceed 450 mg/day
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | 1 mEq/kg every 10 minutes |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | • Analgesic/antipyretic: 325 - 650 mg PO q 4 hours as needed • Acute MI: 325 mg (or 4 x 81 mg chewable tablets to facilitate sublingual absorption and to expedite antiplatelet activity)
 • Thromboembolic disorders: 325 - 650 mg PO QD or BID
 • MI prophylaxis: 81 - 325 mg PO QD
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | • 75 mg PO QD is recommended • For ACS with or without PCI, load with 300 mg and then continue with 75 mg daily
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Hypertension • PO: 5 mg/day; may increase to 10 to 40 mg/day in 1-2 divided doses
 • IV: 1.25 mg slow IV push over 5 minutes every 6 hours; may give up to 5 mg every 6 hours in hypertensive emergencies
 • CHF: 2.5 mg PO QD or BID; may increase up to 5 to 20 mg/day in 1 to 2 divided doses (max of 40 mg/day
 |  | 
        |  |