Shared Flashcard Set

Details

Anticoag
Blood
22
Other
Not Applicable
09/20/2014

Additional Other Flashcards

 


 

Cards

Term
Clotting Trifecta
Definition
  • Vessel damage
  • Blood stasis
  • Disease
Term
Heparin MOA
Definition
Bind Antithrombin
Term
Fondaparinux MOA
Definition
Bind to Antithrombin
Term
How does LMWH differ from Heparin
Definition
  • LMWH: Inhibits 10a > 2a 
  • Heparin: No renal limitation
  • LMWH: B.  Heparin: C
Term
Argatroban MOA
Definition

IV direct thrombin inhibitor 

 

(↓ amount of fibrin for clot formation) 

Term
Thrombin AKA
Definition
Factor II
Term
Dabigatran MOA
Definition
Oral Direct Thrombin Inhibitor
Term
Warfarin Factors
Definition
2, 7, 9, 10
Term
HIT
Definition

5-14D

Platelet drop by 50%

Term
Heparin factors
Definition
2a (Thrombin), 10a, 9a, 6a, 7a, Plasmin
Term
Heparin prophylaxis dose
Definition
5000U SC Q8-12H
Term
Heparin Monitor:
Definition

aPTT

(1.5-2.5 x baseline)

Term

LMWH Dose

  • Prophylaxis
Definition
  • 30mg SC BID or 40mg QD
  • Crcl <30: 30mg SC QD
Term

LMWH

  • Treatment
Definition
  • 1mg/kg SC BID or 1.5mg/Kg SC QD
  • Crcl <30: 1mg/Kg SC QD
Term
LMWH Monitor
Definition
Anti-Xa levels
Term
Rivaroxaban Dose
Definition

A. Fib: 15-20mg QD with evening meal

 

Note: DVT no regard to meals

Term
Apixaban Dose
Definition
5mg BID
Term
Rivaroxaban Black Box
Definition
  • CI if Hx spinal puncture
  • Don't abruptly stop
Term
Dabigatran Dose
Definition

150mg PO BID

 

Better than Warfarin for non-valv A. Fib

Term
When should Vitamin K be given?
Definition
INR >10
Term
Vitamin K AKA
Definition
Phytonadione (Mephyton)
Term
How long is Dabigatran good for?
Definition
4M
Supporting users have an ad free experience!