Term
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Definition
| the first isotype to be expressed in every B cell; occurs in serum as pentamer; can activate compliment cascade; mainly in blood or in low levels in secretions |
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Term
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Definition
| the most abundant Ig sublcass found in human serum; occurs as a monomer; can opsonize antigen for uptake by phagocytic cells; can activate complement cascade; can cross placenta and protect offspring; found in blood and tissues |
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Term
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Definition
| major subclass of Ig in external secretions and mucosa; occurs in serum as a monomer and occurs in secretions as a dimer; found in blood and secretions; found in tears, saliva, and breastmilk |
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Term
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Definition
| occurs in very low concentrations in the serum; can bind to mast cells and basophils and mediates allergies |
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Term
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Definition
| occurs primarily as surgace Ig; co - expressed with IgM; function unknown |
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