Shared Flashcard Set

Details

antibiotics
antimicrobials
36
Medical
1st Grade
11/04/2008

Additional Medical Flashcards

 


 

Cards

Term
phenoxymethpenicillin is what class of antiobiotic and used for what?
Definition
G+ve, penicillin
Term
ampicillin is not useful against what?
Definition
staph and other betalactamase producing organism
Term
cephalothin is what generation of cephalosporin?
Definition
1st
Term
cephalexin is what generation of cephalosporin?
Definition
1st
Term
ceftazidime is what generation of cephalosporin?
Definition
3rd
Term
cefotetan is what generation of cephalosporin?
Definition
2nd
Term
3rd gen cepthalosproins are good for what
Definition
majority of g-ve rods, able to cross CSF
Term
what % of people are sensitive to penicillin
Definition
1-10%
Term
what geration of cephalosproins are used for prophylactic antimicrobial for bowel & gynacological surgery? what are 2?
Definition
2nd generation cefoxitin cefotetan
Term
what % of penicliiin hypersensitivity pt have cross sensitivity to cephalosporins
Definition
3-6
Term
what is a AE of cephalosporins
Definition
bleeding
Term
what are common ae of penicillins
Definition
diarrhoea, nausea
Term
doxycyclin is what type of antiobiotiuc, static or cidal?
Definition
static, tetracycline
Term
what drugs should be avoided in paeds, due to teeth an bone stippling
Definition
tetracyclines
Term
gentamycin is a what, what are 2 problems affecting use?
Definition
nephrotoxicity and ototoxicity, due to narrow therapeautic window
Term
amikacin is is what type, what is it used for
Definition
aminglycoside, wide incling pseudomanas
Term
how do aminoglycoside work
Definition
inhibit protein syntheis by irreversibly binding to 30s ribosomes
Term
what are the ab to cause achilles tendonitis
Definition
quinolones
Term
what a important podiatric ae ass with ciprofloxacin
Definition
its a quinolones so achilles tendonitis
Term
how do quinolones work
Definition
inhibit dna gyrase and topoisomerase
Term
what are cautions of quinolones
Definition
damage joint in immature animals so dont give to kids less than 14, absorption interactions
Term
what are quinolones active against
Definition
give, enteric g-ve rods (pseudomonas), g-ve cocci, mycobacteria
Term
what are quinlones know to have poor activity agaisnt strept
Definition
Term
erythromycin is what type of antiobitoic and how does it act
Definition
binds 5-s ribosomes inhibt protein snythesis (a macrolide)
Term
Rickettsia(scrub typhus), Mycoplasm, Chlyamydia, & Plasmodium(e.g.malaria) are effectively treated with
Definition
tetracyclines
Term
Quinilones have poor activity against
Definition
strept
Term
which of the following is not true of vancomycin?

inhibits prtein synthesis.has a narrow spectrum against Gram + & anaerobic organisms, sounds like an aminoglycoside but isn't. causes oto & nephrotoxicity.
Definition
inhibit pretin sythesi, it inhibits cell wall sythesis
Term
Pseudomembraneous colitis is a serious adverse effect in up to 10% of patients treated with
Definition
clindamycin.
Term
rashes and bone marrow depression of ae of what
Definition
sulfonamides
Term
woulde clarithromyci be a good treatment for a pseudomonas infection?
Definition
no
Term
rifampicin acts how... ad used in the px and rx of what
Definition
inhibit bacterial rna polymerase, meningococcol dz.. also use on staph and mucobacteria
Term
clindamycin is particulary useful in what? and is cidal or static.... act how
Definition
post ortho and dental , static, cell wall synthesis
Term
name a lincosmaide
Definition
clindamycin
Term
vancomyci is what type of antibiotic.... cidal or static/
Definition
glycopeptide, cidal
Term
vancomycin is particularily used for what?and what microbes
Definition
MRSA, g+ve aerobic and anaerobic
Term
vancomycin is a aminoglycoside which causes oto-and nephrotoxicity t or f
Definition
f does cause that but it is a glycopeptide
Supporting users have an ad free experience!