Term
| what stage of bacterial growth do fluoroquinolones, rifampin, and metronidazole act at |
|
Definition
|
|
Term
| what part of bacteria do polymyxins and amphotercins attack? |
|
Definition
|
|
Term
| T or F clcloserine is an irreversible inhibitor of PBP |
|
Definition
| F it is reversible- penicillin is irrevrsible |
|
|
Term
| T or F Methicillin, nafcillin, oxacillin, and cloxacillin are pencillinase-resistant |
|
Definition
|
|
Term
| how does Vancomycin inhibit bacteria |
|
Definition
| by inhibiting cell wall synthesis |
|
|
Term
|
Definition
| synergizes with vancomycin |
|
|
Term
| T or F E. faecalis can be resistant to vancomycin and all other antibiotics |
|
Definition
|
|
Term
| what are streptogramins used to treat |
|
Definition
| Vancomycin resistant gram + infections |
|
|
Term
| what are oxazolidinones used to treat and what is the mechanism |
|
Definition
| Vancomycin resistant gram + infections- they interfer with the bact. ribozyme |
|
|
Term
| What is the action of aminoglycosides |
|
Definition
| they inhibit the bacterial ribozyme |
|
|
Term
| what is the action of sulfonamides and trimethoptrim drugs |
|
Definition
| they inhibit bacteria's ability to synthesize folate at two different sites |
|
|
Term
| T or F sulfonamides are bacteriocidal |
|
Definition
| False- they are bacteriostatic after a delay |
|
|
Term
| what drug is a broad spectrum that can be used to treat rickettsia and chlamydia; adverse effects are retardation of bone and photophobia |
|
Definition
|
|
Term
| wwhat drug can be used to treat legionella, camplobacter, mycoplasma and all the drugs in the class end in omycin |
|
Definition
| erythromycin (class Macrolides) |
|
|
Term
| what is the major adverse reactions of chloramphenicol |
|
Definition
| reversible bone marrow depression and aplastic anemia that is FATAL and not dose-related |
|
|
Term
| What class antibiotics act by inhibiting DNA synthesis by blocking DNA gyrase- all drugs end in -floxacin |
|
Definition
|
|
Term
| what drug is used to treat anaerobic trichomoniasis by reducing its nitro group that subsequently splits bact. DNA |
|
Definition
|
|
Term
| What antibiotics are active against poolymyxin B and E; they act by disrupting bacterial membrane |
|
Definition
|
|
