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Antiarrhythmic Drug Classificiations
common antiarrhythmic drugs
21
Medical
Graduate
09/22/2012
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Term
Quinidine
 Definition
Class IA
Term
Procainamide
 Definition
Class IA
Term
Disopyramide
 Definition
Class IA
Term
Lidocaine
 Definition
Class IB
Term
Mexiletine
 Definition
Class IB
Term
Flecainide
 Definition
Class IC
Term
Propafenone
 Definition
Class IC
Term
Propanalol
 Definition
Class II
Term
Esmolol
 Definition
Class II
Term
Metoprolol
 Definition
CLass II
Term
Amiodarone
 Definition
Class III
Term
Sotalol
 Definition
Class III
Term
Ibutelide
 Definition
Class III
Term
Dofetilide
 Definition
Class III
Term
Verapamil
 Definition
Class IV
Term
Diltiazem
 Definition
Class IV
Term
What do Class IA drugs do?
 Definition
Na channel moderate block
decrease phase 0 upstroke rate
prolong AP duration
Term
What do Class IB drugs do?
 Definition
Mild Na channel block
decrease phase 0 upstroke
Shorten AP duration
Term
What do Class IC drugs do?
 Definition
Marked block of Na channel
severely decreased phase 0 upstroke
no change in AP duration
Term
what do Class III drugs do?
 Definition
prolong the AP duration
primarily through K channel block
Term
what do class IV drugs do?
 Definition
calcium channel antagonists
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