Term
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Definition
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Definition
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Term
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Definition
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Term
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Definition
parenteral preparation used for iron deficiency anemia
-administered by deep intramuscular injection or IV (most common) |
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Term
| sodium ferric gluconate complex |
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Definition
parenteral preparation used for iron deficiency anemia
-administered only by IV |
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Term
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Definition
| parenteral preparation used for iron deficiency anemia |
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Term
| adverse effects of oral Fe therapy |
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Definition
nausea
epigastric discomfort
abdominal cramps
constipation
diarrhea
black stool (no clinical significance - may hide blood loss diagnosis) |
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Term
| adverse effects of parenteral Fe therapy |
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Definition
| chronic treatment necessitates monitoring of Fe storage levels to avoid toxicity of iron overload |
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Term
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Definition
seen in young children accidentally ingesting Fe tablets
-urgent treatment - flush out unabsorbed pills
-systemic administration of Fe antidote |
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Term
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Definition
Fe overload/hemochromatosis
organ failure/death
treat: intermittent phlebotomy in absence of anemia
-administration of iron antidote |
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Term
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Definition
Fe antidote (iron chelator)
-low oral availability
-administered IM and IV
-used in iron poisoning, transfusional Fe overload |
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Term
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Definition
Fe antidote (tridentate iron chelator)
-administered orally
-used in chronic iron overload due to blood transfusions |
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Term
deoxyadenosylcobalamin
methylcobalamin |
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Definition
active form in humans
-can have various organic groups covalently bound to the cobalt atom; forms different cobalamins
-Vitamin B12 |
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Term
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Definition
| allows determination of the mechanisms of the vitamin B12 deficiency |
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Term
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Definition
vitamin B12 preparation
-used in vitamin B12 deficiencies |
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Term
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Definition
| vitamin B12 preparation -used in vitamin B12 deficiencies -administered parenterally |
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Term
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Definition
treatment/prevention of megaloblastic anemia caused by folic acid deficiency
-administered orall
-prevents fetal neural tube defects (administered to pregnant women) |
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Term
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Definition
blocks conversion of folic acid into dihydrofolate which depletes the folic acid cycle which halts DNA synthesis and in turn stops cell division
-"Leucovorin Rescue" |
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Term
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Definition
used to treat anemia, primary bone marrow disorders, hemochromatosis... etc
-parenteral administration (3X/week) |
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Term
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Definition
1-2 doses/month
-long lived
used to treat anemia, primary bone marrow disorders, hemochromatosis... etc
-parenteral administration |
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Term
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Definition
1 dose/week
used to treat anemia, primary bone marrow disorders, hemochromatosis... etc
-parenteral administration |
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