Term
| Central A2 agonist prototype |
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Definition
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Term
| Clonidine/Catapres Effects |
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Definition
| Stimulate A2 receptors in the brain which decreases SNS to periphery. Inhibits Norepinephrine release |
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Term
|
Definition
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Term
|
Definition
| Sedation, drowsiness lethargy, hypotension, ortho hypo, and weight gain. Impotence and ejaculatory dysfunction. Rebound HTN |
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Term
|
Definition
| Take in PM R/T sedation. Monitor weight. Counsel for sexual dysfunction. Rise slowly. Taper dose, monitor for rebound HTN, hard candy for dry mouth. |
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Term
| Peripheral A1 blocker prototype |
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Definition
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Term
|
Definition
| Blocks A1 receptors on arteriolar smooth muscle causing vasodilation. Triggers a slight reflexive tachycardia |
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Term
|
Definition
| HTN when other meds are contraindicated |
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Term
|
Definition
| Acute hypotension with early therapy (sedation, lethargy, weight gain, sexual dysfunction) |
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Term
|
Definition
| Take in PM. Monitor Weight. Counsel for sexual dysfunction. First dose can cause fainting! |
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Term
| Calcium Channel Blocker Prototype |
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Definition
|
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Term
|
Definition
| Smooth muscle relaxation by blocking calcium binding to receptors, which prevents muscle contraction. |
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Term
|
Definition
| Angina, HTN, dysrhythmias, migraines |
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Term
|
Definition
| hypotension, constipation, peripheral edema |
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Term
|
Definition
| Teach to increase fluids and fiber foods; take before meals, limit caffeine. |
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Term
|
Definition
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Term
|
Definition
| Inhibit ACE from converting Angiotension I to II, thus indirectly decreasing levels of aldosterone |
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Term
|
Definition
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Term
|
Definition
| Acute hypotension with early therapy |
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|
Term
|
Definition
| Report signs of renal failure (increased weight, decreased urine output, edema) |
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|
Term
| Angiotensin II inhibitor prototype |
|
Definition
|
|
Term
|
Definition
| blocks the binding of angiotension II thus indirectly decreasing levels of aldosterone |
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|
Term
|
Definition
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Term
|
Definition
| Parkinson's syndrome, suicidal depression, gynecomastia, ulcers |
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|
Term
|
Definition
| Take in AM, avoid K+ in sodium substitutes |
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