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| What are the only two statins that are prodrugs |
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| Which statin does not go through the P450 pathway |
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| When is hepatic glucose synthesis the highest |
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| which statins are non-lipophilic agents |
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| pravastatin, rosuvastatin |
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| Bile acid sequestrants have an absolute contraindication when TG are at what level |
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| Which bile acid sequestrant comes in both a powder and a pill form |
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| How do you decrease the incidence of bloating and dyspepsia |
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| suspend the powder in liquid for several hours |
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| How do you reduce constipation that comes with bile acid sequestrants |
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| maintain adequate intake of water and add psyllium (fiber) |
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| How far should you separate administration of bile acid sequestrants with other drugs |
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| 1 hour before or 3-4 hours after |
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| which bile acid sequestrant has been proven to lower A1c in DM |
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What is the most common side effects of bile acid sequestrants?
(A) Myalgias and rhabdomyolysis
(B) Nausea and vomiting
(C) Bloating and constipation
(D) Diarrhea and dehydration |
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| bloating and constipation |
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| What are 2 absolute contraindications with niacin |
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| active liver disease, history of PUD |
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| niacin may negatively affect which two lab values |
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| What is the starting and target doses for niacin |
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| 500, 1500-2000. advance by 500mg/month |
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| What is the only drug that truly treats low HDL |
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| What is the most common adverse effect with niacin and how can it be reduced |
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| flushing/puritis. give ASA 30mins prior to niacin |
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| reduction of LDL by ______% may be a sign of niacin toxicity |
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Mr. F was started on Niaspan ® 500mg at bedtime by his PCP 6 weeks ago. His lipids are not at desired goal yet. What is the correct titration strategy for Mr. F?
(a) Increase Niaspan® to 500mg BID
(b) Increase every 7 days by 100mg
(c) Increase to target dose of 2000mg daily
(d) Increase Niaspan® to 750mg daily |
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| Increase Niaspan® to 500mg BID |
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Tricor
Triglide
Lofibra
TriLipix |
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| which fenofibrate is contraindicated in pts with gallbladder disease |
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| ezetimibe is contraindicated in which pts |
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| With which class of drugs does ezetimibe have a synergistic effect at lowering LDL |
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| What are the omega-3 fatty acids |
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| How can you reduce the fishy aftertaste of fish oils |
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