Term
| Types of pathogenic fungi |
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Definition
Yeasts - Candida
Molds - Aspergillis
Dermatophytes - Microsporum, Epidermophyton, Trichophyton
Common infections
sclap ringworm tinea capitis
ringworm tinea corporis
athlete foot tinea pedis
jock itch - tinea cruris |
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Term
|
Definition
| bind ergosterol to form pores which allow ions and macromolecules to leak out of cell |
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Term
|
Definition
miconazole
clotrimazole
sulconazole
tioconazole
terconazole
butoconazole
ketoconazole |
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Term
|
Definition
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|
Term
|
Definition
fluconazole
itraconazole
ketoconazole |
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Term
|
Definition
| prevent ergosterol synthesis via the inhibition of a fungal CYP 450 |
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Term
|
Definition
Candida albicans
Microsporum
Epdermophyton
Trichophyton
Pityrosporum - tinea versicolor |
|
|
Term
|
Definition
accumulates in keratin cells - covers all tinea
MOA - inhibits fungal mitosis by binding polymerized microtubutles
decreased use as terbinafine and fluconazole are now used |
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Term
|
Definition
PO and topical
acts against all MET fungi
MOA: prevents ergosterol synth by inhibiting squalene epoxidase, acc of squalene kills the fungal cells
drug accumulates in skin nails, and fat cells
pregnancy category B |
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Term
|
Definition
topical prescription
MOA same as terbenafine
covers MET |
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Term
|
Definition
topical OTC
MOA unknown
covers MET and P. orbiculare |
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