Mechlorethamine

• MOA
• Specific?

• Alkylating agent
• Nonspecific

Cyclophosphamide

• MOA
• Specific?

• Alkylating agent
• Nonspecific

Carmustine

• MOA
• Specific?

• Alkylating agent
• Nonspecific

Cisplatin

• MOA
• Specific?

• Alkylating agent
• Nonspecific

Methotrexate

• MOA
• Specific?

• Folate analog
• S

Mercaptopurine

• MOA
• Specific?

• Purine analog
• S

Fluorouracil

• MOA
• Specific?

• Pyrimidine analog
• S

Cytarabine

• MOA
• Specific?

• Antimetabolite
• S

Daunorubicin HCl

• MOA
• Specific?

• Binds and uncoils DNA (Antibiotic)
• Nonspecific

Doxorubicin HCl

• MOA
• Specific?

• Binds and uncoils DNA (Antibiotic)
• Nonspecific

Vinblastine Sulfate

• MOA
• Specific?

• Disrupts mitotic spindles
• M

Vincristine Sulfate

• MOA
• Specific

• Disrupts mitotic spindles
• M

Etoposide

• MOA
• Specific?

• Topoisomerase inhibitor
• G2

Paclitaxel

• MOA
• Specific?

• Antimicrotubule (promotes)
• G2 & M

Tamoxifen

• MOA
• Specific?

• Competes with estradiol
• G1

Imatinib

• MOA
• Specific?

• Tyrosine kinase.  Proliferation inhibitor.  Cell apoptosis

Trastuzumab

• MOA
• Specific?

• Monoclonal.  Binds GF.  Cell frozen in G1

Daunorubicin HCl

Doxorubicin Hcl

(seeing those double Ds make my heart hurt)

• Paclitaxil
• Etoposide

(I drink G2 for PE)