Term
Procainamide
lidocaine
flecanide |
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Definition
All 3 Na channel blockers plus procainamide is k channel blocker. Lidocaine weakest, flecanide strongest.
Highest affinity when Na Channel open
prevents re-entry tachycardia and delays DADS.
Increases QRS interval, may causes mono-Vtac via increase in calcium lvls
(QRS=ventricular conduction by NA, QT is ventricular repolarization by K)
procainamide may also causes torsalsdepoints (early after depolar) via k.
Lidocaine: small negitive ionotrope, supress vtac
Flecainide: huge negitive ionotrope drug of choice low risk a fib (pocket)
procainimide:use vtac may cause lupup-like |
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Term
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Definition
Beta-adrenergic antagonist PR interval
used to control RATE via AV node
good for excess calcium
also used for rhythem control
avoid in patients with AV node block
(only ventricular rate) |
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Term
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Definition
RHYTHM: Increases QT interval via K channels
amidarone = used for cardiac arrest
low risk pro-arrytmias, good prophylaxis
blocks k (but also Na and Ca)
builds up in skin, bronchotoxic, optic neuropathy. THYROTOXICOSIS
increases blood lvls digoxin/warfarin
long t1/2 means recognize se early |
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Term
| Verapimil (antiarrythmic) |
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Definition
-stops Ca for conduction across AV node thereby increasing PR interval
used for RATE and AV-RT
(stops depolarization from occuring during RRR) |
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Term
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Definition
SVT re-entry stopper via hyperpolarization and temporary cardiac arrest.
A1 = down SA/AV
A2 = vasodilation
A3 = mast cells flushing
(k channel activation)
AVOID ASTHMA!!!! |
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Term
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Definition
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Term
| Structural heart disease for anti-arrythmics |
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Definition
amiodirone
low co = amiodirone and lidocaine |
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Term
Afib rhytem
afib rate
vtac
av rentry |
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Definition
amiodarone, sotalol, flecainide
propanolol, verapamil
amiodarone, lidocaine, procainamide
adenosine/verapamil |
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Term
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Definition
1 a-Procain
1 b -lido
1 c - flecaanide
2 propanol0l
3. amiodarone
4. verapamil |
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Term
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Definition
Increases QT interval via K channels, d form also b antagoinst
Sotalol: prophylaxis for Afib/vtac with coexisting ischemia. drops # shocks implanted defib.
negitive ionotrope, pro torsades de points via K |
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Term
| Abnormally long action potentials |
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Definition
| early after depolarizations --> torsal de points --> tx is shorten action potential |
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Term
| Delayed Action potential myo toxicity |
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Definition
premature ventricular contractions -->
relieve Ca overload |
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Term
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Definition
rhythem: better hemodynamics decreased thromboembolism but more toxic
rate: better success, prolonged anticoag |
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