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Anti-anxiety
Pharm II
68
Pharmacology
Graduate
08/28/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
inhibitory in nature via the GABA receptor
Definition
Benzodiazepines
Term
Oxazepam (Serax)
Definition
Short acting Benzo- ETOH withdrawal
Term
Triazolam (Halcion)
Definition
Short acting Benzo
Term
Midazolam (Versed)
Definition
Short acting Benzo- Amnesia
Term
Alprazolam (Xanax)
Definition
Intermediate Acting Benzo- panic attacks
Term
Temazepam (Restoril)
Definition
Intermediate Acting Benzo
Term
Lorazepam (Ativan)
Definition
Intermediate Acting Benzo- ETOH withdrawal
Term
Diazepam (Valium)
Definition
Long acting Benzo- muscle relaxation; DOC grand-mal seizures, ETOH withdrawal
Term
Flurazepam (Dalmane)
Definition
Long acting Benzo
Term
Clonazepam (Klonopin)
Definition
Long acting Benzo- Chronic epilepsy
Term
Chlordiazepoxide (Librium)
Definition
Long acting Benzo- ETOH withdrawal
Term
Clorazepate (Tranxene)
Definition
Long acting Benzo- ETOH withdrawal
Term
Flurazepam (Dalmane)
Definition
LA Sleep disorder Benzo
Term
Temazepam (Restoril)
Definition
IA Sleep disorder Benzo
Term
Triazolam (Halcion)
Definition
SA Sleep disorder
Term
Flumazenil (Romazicon)
Definition
Benzo Antagonist- for rapid reversal and overdose
Term
Buspirone (BuSpar)
Definition
stimulates 5-HT 1A receptors- for general anxiety disorder
Term
Hydroxyzine (Atarax, Vistral)
Definition
Antihistamine & Antiemetic- for sedation
Term
Eszopiclone (Lunesta)
Definition
Sedative/Hypnotic Agents- Acts on subset of Benzo site (BZ1) on GABA receptors, withdrawal or tolerance develops, no anticonvuslant or muscle relaxation
Term
Ramelteon (Rozerem)
Definition
Sedative/Hypnotic Agents- Melatonin MT1 and MT2 receptor agonist
Term
Zalepon (Sonata)
Definition
Sedative/Hypnotic Agents- Acts on subset of Benzo site (BZ1) on GABA receptors, NOT metabolized by CYP3A4
Term
Zolpidem (Ambien, Zolpimist)
Definition
Sedative/Hypnotic Agents- Acts on subset of Benzo site (BZ1) on GABA receptors, no withdrawal or tolerance, requires CYP3A4- several AE
Term
replaced benzo for sedation, induction and maintenance of sleep
Definition
Barbiturates
Term
Barbiturates
Definition
increase GABA action of chloride through non- benzo site, block glutamate receptors and NA channels, decrease mesencephalic reticular activating system
Term
Chloral Hydrate
Definition
non barbiturate sedative
Term
antihistamines
Definition
non barbiturate sedative
Term
ETOH
Definition
non barbiturate sedative
Term
Disulfiram
Definition
quit drinking
Term
NAltrexone
Definition
opiate antagonist
Term
Methylzanthines
Definition
psychomotor stimulants- phosphodiesterase inhibitors, adensoine receptor antagonists
Term
caffeine
Definition
Methylzanthine
Term
Theophylline
Definition
Methylzanthine
Term
Nicotine
Definition
psychomotor stimulant- CNS and ganglionic stimulation
Term
Cocaine
Definition
psychomotor stimulants, blockade of NE, serotonin & DA reuptake
Term
Amphetamine
Definition
psychomotor stimulants- release intracellular stores of catecholamines and blocks MAO
Term
Methylphenidate- ritalin
Definition
Amphetamine
Term
Lysergic Acid Diethylamide (LSD)
Definition
Psychotomimetics Stimulant- ergot, serotonin agonist
Term
tetrahydrocannabinol (Dronabinol)
Definition
Psychotomimetics Stimulant- marijuana
Term
phencyclidine (PCP)
Definition
Psychotomimetics Stimulant- NMDA antagonist receptor blocker, inhibits reuptake of dopamine, 5ht & NE
Term
Bupropion SR (Zyban)
Definition
smoking cessation, antidepressant
Term
Varenicline (Chantix)
Definition
smoking cessation- most effective drug
Term
Benzodiazepines used in Anesthetics
Definition
Diazepam, Lorazepam, and Midazolan
Term
Opioids used in Anesthetics
Definition
morphine, meperidine, fentanyl
Term
anticholinergics used in Anesthetics
Definition
scopolamine
Term
Antiemetics used in Anesthetics
Definition
droperidole, metoclopramide
Term
Thiopental
Definition
anesthesia induction agent, SA barbiturate not available anymore
Term
etomidate (amidate)
Definition
anesthesia induction agent, work on GABA receptor complex
Term
Propofol (Diprivan)
Definition
anesthesia induction agent, work on GABA receptor complex
Term
Ketamine
Definition
NMDA antagonist- Produces a dissociated state in which the patient appears awake but is unconscious and does not feel pain
Term
Vecuronium
Definition
Non depolarizing Neuromuscular blockers
Term
Pancuronium
Definition
Non depolarizing Neuromuscular blockers
Term
tubocurarine
Definition
Non depolarizing Neuromuscular blockers
Term
Atracurium
Definition
Non depolarizing Neuromuscular blockers
Term
Succinylcholine
Definition
Depolarizing Neuromuscular blocker
Term
Halothane
Definition
Halogenated gas, inhalation anesthetic- potent anesthetic but weak analgesic
Term
Enflurane
Definition
Halogenated gas, inhalation anesthetic-
Term
Isoflurane
Definition
Halogenated gas, inhalation anesthetic- bronchial irritant/ salivation, no cardiac arrhythmias and no catechol sensitization
Term
Desflurane
Definition
Halogenated gas, inhalation anesthetic- bronchial irritant/salivation, expensive, warm up
Term
Sevoflurane
Definition
Halogenated gas, inhalation anesthetic- rapid uptake and minimal airway irritation
Term
Dantrolene
Definition
reversal agent for halogenated gases
Term
Nitric Oxide
Definition
inhalation anesthetic, never acheive stage III on its own
Term
IV anesthetics- Barbiturates
Definition
thipental, thamylal, methohexital
Term
IV anesthetics- Benzodiazepines
Definition
lorazepam, midazolam
Term
IV anesthetics- opiods
Definition
Fentanyl
Term
IV anesthetics- neurolept anesthesia
Definition
droperidol/fentanyl (innovar)
Term
Local anesthetics
Definition
Inhibit sodium channels of the peripheral nerve membranes which slows the rate of depolarization of the nerve action potential
Term
Local anesthetic- Esters
Definition
procaine, chloroprocaine, tetracaine, cocaine
Term
Local anesthetics- Amides
Definition
mepivavaine, lidocaine, ropicacaine, bupivacaine, bevobupivacaine, etidocaine
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