Term
|
Definition
|
|
Term
|
Definition
| Receptors found on sympathetic and parasympathetic post-ganglionic neurons and on chromaffin cells of the adrenal medulla. |
|
|
Term
1. Post-ganglionic sympathetic neurons 2. Post-ganglionic parasympathetic neurons 3. Chromaffin cells of the adrenal medulla |
|
Definition
| Where are Nn cholinergic receptors found? |
|
|
Term
|
Definition
| Receptor found at the motor endplate of skeletal muscles |
|
|
Term
|
Definition
| Receptor found at the parasympathetic target organs, also found in the sweat glands. |
|
|
Term
|
Definition
| This structre secretes epinephrine |
|
|
Term
| The sweat gland is the only receptor that binds Ach to elicit a sympathetic response. |
|
Definition
| Why is the sweat gland unique? |
|
|
Term
1. blood vessels 2. sweat glands 3. kidney 4. adrenal medulla |
|
Definition
| Organs or areas that are innervated by sympathetic only (4). |
|
|
Term
| CN 3, 7, 9, 10 of the parasympathetic |
|
Definition
| Cranio out flow is what nerves? of what system? |
|
|
Term
1. bladder 2. genitalia 3. lower bowels S2, S3, S4 |
|
Definition
| Sacral outflow innervates what 3 things? What levels do they originate from? |
|
|
Term
|
Definition
| Levels of outflow of the sympathetic nervous system |
|
|
Term
| Intermediolateral horn of the spinal cord. They exit the cord via the ventral roots. |
|
Definition
| Where, in the spinal cord, do the cell bodies of the sympathetic neurons originate? Which side do they exit? |
|
|
Term
1. synapse on the sympatheic chain gain. 2. go up or down the chain to synapse. 3. pass thru the ganglia (unsynapsed) and synapse on a visceral ganglia |
|
Definition
| The 3 options that a sympathetic nerve can do about synapsing. |
|
|
Term
|
Definition
|
|
Term
| Sympathetic nervous system |
|
Definition
| Noxious stimuli, such as excessive stretch, is communicated to CNS via _______. |
|
|
Term
| Parasympathetic nervous system |
|
Definition
| Physiologic conditions such as stretch, temp, pH, hypoxia are communicated to the CNS via ______. |
|
|
Term
|
Definition
| Sympathetic activity is always on in ____ ____. It can be increased or decreased. |
|
|
Term
|
Definition
| ____ activity is always on to the heart. |
|
|
Term
|
Definition
| Pupil constriction mediated by the parasympathetic response circular sphincter muscle. |
|
|
Term
|
Definition
| Pupil dialation mediated by the sympathetic response of the radial muscle. |
|
|
Term
|
Definition
| Gland that is atypical in that it is innervated by both the sympathetic and parasympathetic. |
|
|
Term
|
Definition
| Binds to ALL pre-ganglionic receptors and post-ganglionic parasympathetic receptors. |
|
|
Term
|
Definition
| Released from sympathetic post-ganglionic neurons |
|
|
Term
1. Sympathetic cholinergic innervations of sweat glands 2. Dopaminergic innervations of renal blood vessels causing renal dilation. |
|
Definition
| 2 exceptions in the ANS neurotransmission |
|
|
Term
|
Definition
| Binding of ____ to this receptor___ causes contraction of smooth muscle found in blood vessels, GI and bladder sphincters, and radial muscle of iris. |
|
|
Term
Gq mediated activation of phospholipase C -->increased production of IP3 --> increased levels of intracellular Ca++ Gq--> activated phospholipase C--> higer IP3--> higher Ca++ in cell |
|
Definition
| Mechanism of action of Alpha 1 receptor |
|
|
Term
| Gi protein mediated inhibition of adenyl cyclase--> this leads to decreased levels of cAMP |
|
Definition
| Mechanism of action of Alpha 2 |
|
|
Term
| Gs stimulates adenyl cyclase--> increased cAMP |
|
Definition
| Mechanism of action of Beta 1 receptors |
|
|
Term
|
Definition
| Stimulates the heart and juxtaglomerular cells of the kidney that produce renin. |
|
|
Term
|
Definition
| Stimulates relaxation of the bronchioles and skeletal muscle blood vessels |
|
|
Term
| Gs protein stimulation of adenlyl cyclase --> converts ATP to increase cAMP |
|
Definition
| Mechanism of action of Beta 2 receptors |
|
|
Term
Beta 1, than Alpha 1 Stimulates the heart and the kidney |
|
Definition
| Catechcolamines are more potent at _____ receptors than at ____ receptors. Thus, the epinephrine release produces more of a ____ response. |
|
|
Term
|
Definition
| Norepi and epi have equal potencies at _____ receptors |
|
|
Term
|
Definition
| Epinephrine is more potent than NorEpi at ____ receptors. |
|
|
Term
|
Definition
Receptor between the pre and postganglionic neurons _______. These are found in the sympathetic and parasympathetic system. It is blocked by this ganglion blocking drug ____. |
|
|
Term
|
Definition
| Nicotinic receptors are ____ gated ion channels. |
|
|
Term
|
Definition
| Receptor located on the sweat glands and the parasympathetic smooth muscle and glands. |
|
|
Term
| Gprotein mediated increase of IP3--> increase in Ca++ in the cell. |
|
Definition
| Mechanism of action of muscarinic receptor |
|
|
Term
|
Definition
| 2 ways that neurotransmitters are degraded. |
|
|
Term
| No, it is broken down too quickly |
|
Definition
| Can Ach be measured in blood plasma? |
|
|
Term
Botulism Myasthenia Gravis, Neostigmine is an AchEsterase inhibitor |
|
Definition
What blocks the release of Ach from the terminal? What disease blocks the Ach receptors? What drug is used to treat and how does it work? |
|
|
Term
|
Definition
| What 2 things can act as a AchEsterase inhibitor? |
|
|
Term
| Tyrosine--> L-dopa--> Dopamine--> NorEpi--> Epinephrine |
|
Definition
| These are precursors of epinephrine |
|
|
Term
|
Definition
| Can epi and norepi be measured in blood plasma and urine? |
|
|
