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ANS Pharmacology
classes of sympathomimetics & cholinergics
15
Biology
Graduate
10/07/2011

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Term
Direct-acting Sympathomimetics
mostly catecholamines
Definition
Epinephrine
Norepinephrine
Isoproterenol
Dobutamine
Albuterol, salmeterol, terbutaline
clenbuterol
dopamine
Term
Indirect-acting sympathomimetics
mostly non-catecholamines
Definition
Amphetamine
Cocaine
Dopamine (catecholamine)
Ephedrine
Tyramine
Term
Alpha-adrenergic antagonist
Definition
Prazosin
Phentolamine
Yohimbine
Tamsulosin
Term
alpha-adrenergic agonist
Definition
Phenylephrine
Clonidine
Term
Beta-adrenergic antagonist
Definition
Metoprolol, atenolol, Esmolol
Propranolol, Timolol
Term
Mixed adrenergic antagonist
Definition
Labetolol
Carvedilol
Term
sympatholytic
(reducer of central sympathetic outflow
Definition
Benzodiazapines (GABA agonist): diazepam
clonidine
Term
Miscellaneous
CCB
vasodilator
Definition
Ca-channel blockers:
diltiazem/verapamil (cardiac>peripheral)
nifedipine/amlodipine (peripheral>>>cardiac)
vasodilators: nitroglycerin (venous>arterial)
Term
Muscarinic Receptor Agonists
Definition
Ach
Pilocaprine
Muscarine
Term
NicotinicN receptor agonist
Definition
Nicotine
Term
Spontaneously reversible cholinesterase inhibitors
Definition
Physostigmine (centrally & peripherally active)
Pyridostigmine (peripherally restriced)
Term
Irreversible Cholinesterase Inhibitory
Definition
Sarin
Term
Cholinesterase reactivator
Definition
2-PAM (pralidoxime)
Term
Muscarinic Antagonists
Definition
Atropine
Scopalamine
Tropicamide
Ipratropium
Term
Neuromusclar blocking drugs
Definition
Succinylcholine
curare
vecuronium, rocuronium
botulinum toxin
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